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Updated: Oct 29, 2025
07:50
Global and Current Research Trends of Single-Cell Sequencing in Cancer: A Bibliometric and Visualization Study
Published on: April 18, 2025
517
Trends in HSPB5 research: a 36-year bibliometric analysis
Zhengdong Xu1, Yehong Gong1, Jiaqian Wan1
1College of Physical Education and Training, Shanghai University of Sport, 399 Changhai Road, Shanghai, 200438, People's Republic of China.
Cell Stress & Chaperones
|July 8, 2021
Summary
This bibliometric analysis reveals global research trends in heat shock protein B5 (HSPB5), also known as αB-crystallin. The study highlights key research topics and publication patterns from 1985-2020.
Area of Science:
- Biochemistry
- Molecular Biology
- Cell Biology
- Neuroscience
- Ophthalmology
Background:
- Heat shock protein B5 (HSPB5), or αB-crystallin, is a prominent small heat shock protein (sHsp). Extensive research exists, but bibliometric analysis is lacking.
- Understanding research trends is crucial for identifying knowledge gaps and future directions in HSPB5 studies.
Purpose of the Study:
- To conduct a bibliometric analysis of HSPB5 research from 1985 to 2020.
- To identify global research trends, influential publications, and key research areas.
Main Methods:
- Bibliometric analysis of publications from the Web of Science Core Collection (WoSCC).
- Data analysis included publication counts, citations, influential journals, leading countries, and keyword co-occurrence.
Main Results:
- 1220 articles published, cited 54,778 times across 391 journals.
- The USA led publications; Journal of Biological Chemistry was the most influential journal.
- Key research themes include HSPB5 expression, chaperone functions, and pathological studies.
Conclusions:
- This bibliometric analysis provides a comprehensive overview of HSPB5 research trends.
- Identifies key research areas and facilitates potential collaborations for future studies.
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