A parallel test of the SCRAM-CAM transdermal monitors ensuring reliability

Area of Science:

• Forensic Science
• Biomedical Engineering
• Alcohol Research

Background:

• Previous validation of transdermal alcohol concentration (TAC) via Secure Continuous Remote Alcohol Monitors Continuous Alcohol Monitoring (SCRAM-CAM) relied on self-reports or breath alcohol concentration (BrAC).
• Limited research exists on the reliability of SCRAM-CAMs when two devices are used concurrently.

Purpose of the Study:

• To assess the reliability of SCRAM-CAM devices by testing two monitors simultaneously.
• To provide further evidence for the accuracy of TAC measurements using SCRAM-CAM technology.

Main Methods:

• Twenty-one participants consumed four standard drinks in a controlled laboratory setting.
• SCRAM-CAM devices were worn on both ankles, sampling TAC every 30 minutes.
• Monitoring continued for 2-3 hours post-BrAC normalization; body mass index (BMI) was calculated.

Main Results:

• A significant positive correlation (r=0.718) was observed between TAC measurements from left and right SCRAM-CAMs.
• Correlations for Area Under the Curve (AUC) and peak TAC values were fair (r=0.554, r=0.579).
• Body Mass Index (BMI) showed a significant effect on the relationship between left and right peak TAC values, potentially due to outliers.

Conclusions:

• SCRAM-CAM devices demonstrate good correlation for TAC measurements when used in pairs.
• While promising for research, further investigation is needed to confirm the reliability of paired TAC monitoring.
• The findings support the potential utility of SCRAM-CAMs in research settings for continuous alcohol monitoring.