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The Association Between Cardio-Ankle Vascular Index and Primary Idiopathic Complete Atrioventricular Block in an

Turhan Turan1, Faruk Kara1, Selim Kul1

  • 1Department of Cardiology, University of Health Sciences, Ahi Evren Cardiovascular and Thoracic Surgery Training and Research Hospital, Trabzon, Turkey.

Angiology
|July 8, 2021
PubMed

Insights

Arterial stiffness, measured by cardio-ankle vascular index (CAVI), is significantly higher in patients with idiopathic complete atrioventricular block (iCAVB). Increased CAVI is an independent predictor of iCAVB, suggesting a link between vascular health and this heart condition.

Area of Science:

  • Cardiology
  • Vascular Medicine
  • Biomedical Engineering

Background:

  • Complete atrioventricular block (CAVB) is often caused by age-related degeneration, termed primary idiopathic CAVB (iCAVB).
  • Arterial stiffness is a known cardiovascular risk factor, but its specific association with iCAVB requires further investigation.

Purpose of the Study:

  • To investigate the relationship between arterial stiffness, assessed using the cardio-ankle vascular index (CAVI), and iCAVB.
  • To determine if CAVI is an independent predictor of iCAVB.

Main Methods:

  • A case-control study involving 41 patients with iCAVB (implanted with dual-chamber pacemakers) and 40 age- and gender-matched controls.
  • Arterial stiffness was measured using the VaSera VS-1000 CAVI instrument.

Main Results:

  • Patients with iCAVB exhibited significantly higher CAVI values compared to controls (9.63 ± 1.42 vs 8.57 ± 1.12, P < .001).
  • The frequency of iCAVB was higher in patients with abnormal CAVI values (P = .04).
  • Multivariate analysis identified CAVI as an independent predictor of iCAVB (OR, 2.575; 95% CI [1.390-4.770]; P = .003).

Conclusions:

  • Elevated CAVI, a marker of arterial stiffness, is associated with iCAVB in elderly patients.
  • Easily measurable CAVI may provide insights into the underlying mechanisms of iCAVB and serve as a potential diagnostic or prognostic tool.

Keywords:
agingarterial stiffnessatrioventricular blockcardio-ankle vascular index

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