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Updated: Oct 29, 2025

Establishment of Cancer Stem Cell Cultures from Human Conventional Osteosarcoma
Published on: October 14, 2016
[Conventional epiphyseal chondrosarcoma of childhood and adolescence: a case report]
R M Mueller1, J Hardes2, A Streitbürger2
1Klinik für Unfall‑, Hand- und Wiederherstellungschirurgie, Klinik für Tumororthopädie, Universitätsmedizin Essen, Hufelandstraße 55, 45147, Essen, Deutschland. roman.mueller@uk-essen.de.
Introduction:
Conventional chondrosarcoma is the second most common primary malignant bone tumor and usually occurs at older adult ages. It is rare in childhood and adolescence.
Case History:
This case report presents the treatment course of a 13-year-old boy with a symptomatic chondrogenic tumor of the right distal femur. Histopathologically, an epiphyseal intermediate-grade chondrosarcoma (G2) was diagnosed.
Discussion:
Based on the following case, potential radiological and histopathological differential diagnoses, such as chondroblastoma or chondroblastic osteosarcoma, are discussed against the background of current standards in orthopedic oncology.
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