Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy01:30

Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy

469
Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
469
Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

486
Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
486
Histology of the Small Intestine01:27

Histology of the Small Intestine

2.3K
The small intestine exhibits a unique histological structure that significantly enhances its function in digestion and nutrient absorption. These structures include circular folds, villi, and various specialized cells that collectively facilitate the digestion of food.
The intestinal lining features transverse folds called circular folds, each housing fingerlike projections known as intestinal villi. These villi are covered by a layer of simple columnar epithelium, also referred to as...
2.3K
Inflammatory Bowel Disease I: Ulcerative Colitis01:27

Inflammatory Bowel Disease I: Ulcerative Colitis

454
Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
454
Vitamins01:30

Vitamins

1.5K
Vitamins, derived from the Latin word for life, are essential organic substances required in small quantities for optimal growth and overall well-being. Unlike other organic nutrients, vitamins don't act as sources of energy or building materials but rather facilitate these nutrients' utilization by the body. Vitamins are predominantly coenzymes, assisting enzymes in specific chemical actions, like the oxidation of glucose for energy involving B vitamins. Most vitamins are not produced...
1.5K
Factors Influencing Drug Absorption: Disease States and Pharmacology01:25

Factors Influencing Drug Absorption: Disease States and Pharmacology

1.0K
Multiple disease states can significantly influence the oral drug absorption process by affecting blood flow and the functionality of the gastrointestinal (GI) system. Various GI diseases, including conditions that alter GI motility, such as diarrhea, decreased acid secretions (achlorhydria), and infections, have been associated with reduced drug absorption.
Substances such as alcohol and specific drugs, including antineoplastics, can also negatively impact drug absorption. For instance,...
1.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A multi-center study of non-invasive colorectal cancer evaluation in cystic fibrosis (NICE-CF).

Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society·2026
Same author

Patients with cystic fibrosis do not have an increased risk of adverse events after endoscopic retrograde cholangiopancreatography: a propensity-matched analysis.

Annals of gastroenterology·2025
Same author

Low prevalence of peptic ulcer disease in hospitalized patients with cystic fibrosis: A national database study.

The American journal of the medical sciences·2024
Same author

The current state of gastrointestinal motility evaluation in cystic fibrosis: a comprehensive literature review.

Translational gastroenterology and hepatology·2024
Same author

A Gastroenterologist's Guide to Care Transitions in Cystic Fibrosis from Pediatrics to Adult Care.

International journal of molecular sciences·2023
Same author

The relationship between colon polyps and colonic diverticulosis: a retrospective review.

Annals of gastroenterology·2023

Related Experiment Video

Updated: Oct 29, 2025

Measurement of Tissue Non-Heme Iron Content using a Bathophenanthroline-Based Colorimetric Assay
05:08

Measurement of Tissue Non-Heme Iron Content using a Bathophenanthroline-Based Colorimetric Assay

Published on: January 31, 2022

5.1K

Iron Deficiency and the Small bowel​.

David Westrich1, Christine Hachem1, Christine Boumitri2

  • 1Division of Gastroenterology and Hepatology, Department of Internal Medicine, Saint Louis University School of Medicine, 1402 South Grand Blvd, St. Louis, MO, 63104, USA.

Current Gastroenterology Reports
|July 8, 2021
PubMed
Summary

This review covers iron deficiency anemia (IDA) and suspected small bowel bleeding (SSBB). It details diagnostic methods like video capsule endoscopy (VCE) and therapeutic strategies, including iron supplementation and other treatments.

Keywords:
Device assisted enteroscopyIron deficiency Anemia (IDA)Iron therapyObscure gastrointestinal bleedingOccult gastrointestinal bleedingVideo capsule endoscopy

More Related Videos

Quantitating Iron Transport Across the Mouse Placenta In Vivo Using Nonradioactive Iron Isotopes
08:45

Quantitating Iron Transport Across the Mouse Placenta In Vivo Using Nonradioactive Iron Isotopes

Published on: May 10, 2022

2.1K
The Caco-2 Cell Bioassay for Measurement of Food Iron Bioavailability
06:34

The Caco-2 Cell Bioassay for Measurement of Food Iron Bioavailability

Published on: April 28, 2022

5.2K

Related Experiment Videos

Last Updated: Oct 29, 2025

Measurement of Tissue Non-Heme Iron Content using a Bathophenanthroline-Based Colorimetric Assay
05:08

Measurement of Tissue Non-Heme Iron Content using a Bathophenanthroline-Based Colorimetric Assay

Published on: January 31, 2022

5.1K
Quantitating Iron Transport Across the Mouse Placenta In Vivo Using Nonradioactive Iron Isotopes
08:45

Quantitating Iron Transport Across the Mouse Placenta In Vivo Using Nonradioactive Iron Isotopes

Published on: May 10, 2022

2.1K
The Caco-2 Cell Bioassay for Measurement of Food Iron Bioavailability
06:34

The Caco-2 Cell Bioassay for Measurement of Food Iron Bioavailability

Published on: April 28, 2022

5.2K

Area of Science:

  • Gastroenterology
  • Hematology

Background:

  • Iron deficiency anemia (IDA) is a common condition.
  • Suspected small bowel bleeding (SSBB) presents diagnostic challenges.

Purpose of the Study:

  • To review current guidelines and therapeutic options for IDA and SSBB.
  • To discuss diagnostic modalities for small bowel evaluation.

Main Methods:

  • Review of recent guidelines on SSBB, IDA, VCE, and DAE.
  • Discussion of advantages and limitations of VCE, DAE, and imaging.
  • Analysis of medical treatment for refractory SSBB.

Main Results:

  • IDA evaluation involves history, physical exam, and laboratory workup.
  • VCE, DAE, and imaging are key for further investigation when initial tests are unrevealing.
  • Iron supplementation is the primary treatment for IDA secondary to SSBB.

Conclusions:

  • Comprehensive evaluation is crucial for diagnosing IDA and SSBB.
  • Treatment strategies are tailored to the underlying pathology.
  • Multimodal approaches including medical, endoscopic, and surgical options may be necessary.