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Obstructive sleep apnea is associated with postoperative dialysis in patients who underwent coronary artery bypass

Hongchang Guo1, Shengwei Wang1, Changwei Ren1

  • 1Department of Cardiovascular Surgery Center, Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart, Lung and Blood Vascular Diseases, Beijing, China.

Annals of Palliative Medicine
|July 9, 2021
PubMed

Insights

Obstructive sleep apnea (OSA) is common after coronary artery bypass grafting (CABG) and is linked to worse kidney function and increased dialysis risk. Early diagnosis and management of OSA are crucial for improving patient outcomes post-CABG.

Area of Science:

  • Cardiology
  • Nephrology
  • Sleep Medicine

Background:

  • Obstructive sleep apnea (OSA) is prevalent in patients undergoing coronary artery bypass grafting (CABG).
  • OSA is associated with increased postoperative complications following CABG.
  • The impact of OSA on renal function and dialysis incidence post-CABG remains under investigation.

Purpose of the Study:

  • To investigate the association between obstructive sleep apnea (OSA) and renal function.
  • To determine if OSA is an independent risk factor for postoperative dialysis after coronary artery bypass grafting (CABG).

Main Methods:

  • Analysis of data from 178 patients undergoing isolated CABG.
  • Utilized polysomnography for OSA diagnosis.
  • Employed multiple linear regression and multivariate logistic regression analyses.

Main Results:

  • 142 patients (79.8%) were diagnosed with OSA (mild or moderate-to-severe).
  • Patients with OSA exhibited decreased estimated glomerular filtration rate (eGFR) and increased creatinine levels compared to non-OSA patients.
  • Dialysis incidence increased with OSA severity, and eGFR and apnea-hypopnea index (AHI) were independent predictors of dialysis post-CABG.

Conclusions:

  • Obstructive sleep apnea (OSA) is associated with impaired renal function in CABG patients.
  • OSA is identified as an independent risk factor for requiring dialysis after coronary artery bypass grafting (CABG).
Abstract

Keywords:
Obstructive sleep apnea (OSA)coronary artery bypass grafting (CABG)dialysisestimated glomerular filtration rate (eGFR)

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