Contrast-induced Nephropathy in Non-cardiac Vascular Procedures, A Narrative Review: Part 1

Juliette Raffort1, Fabien Lareyre2, Niki Katsiki3

  • 1Clinical Chemistry Laboratory, University Hospital of Nice, France | Université Côte d'Azur, CHU, Inserm U1065, C3M, Nice, France.

Insights

Contrast-induced Nephropathy (CIN) is a risk after iodinated Contrast Medium (CM) use in non-cardiac vascular procedures. Awareness and preventive strategies are crucial for managing this complication and improving patient outcomes.

Area of Science:

  • Nephrology
  • Vascular Surgery
  • Radiology

Background:

  • Contrast-induced Nephropathy (CIN) is a significant complication following iodinated Contrast Medium (CM) administration.
  • While often studied in cardiac procedures, CIN also occurs after non-cardiac vascular interventions.

Purpose of the Study:

  • To review the literature on CIN following non-cardiac vascular procedures for aortic aneurysm and carotid stenosis.
  • To discuss CIN's definition, pathophysiology, incidence, risk factors, biomarkers, consequences, and prevention.

Main Methods:

  • Narrative review of existing literature.
  • Focus on diagnostic or therapeutic non-cardiac vascular procedures.

Main Results:

  • CIN is associated with adverse short- and long-term outcomes, including cardiorenal events, extended hospitalization, and mortality.
  • Identified risk factors, biomarkers, and consequences of CIN in specific non-cardiac vascular settings.

Conclusions:

  • Physicians and vascular surgeons must recognize CM-related risks and employ preventive strategies.
  • Further research is essential to better understand and mitigate CIN in these patient populations.

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