Related Experiment Video
Updated: Aug 7, 2026

Proximal Cadaveric Femur Preparation for Fracture Strength Testing and Quantitative CT-based Finite Element Analysis
Published on: March 11, 2017
Computed tomography guidance for skeletal biopsy
D H Frager1, M J Goldman, L P Seimon
1Department of Radiology, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY 10467.
Computed tomographic (CT) guided biopsy is effective for skeletal lesions. This imaging technique provides accurate needle placement and minimizes radiation exposure for physicians during spinal and bone biopsies.
Area of Science:
- Radiology
- Interventional Radiology
- Oncology
Background:
- Computed tomographic (CT) guided biopsy and abscess drainage are established procedures for various organ systems.
- Spinal and skeletal applications of CT guidance are less frequently reported in medical literature.
- Accurate diagnosis of skeletal lesions often requires tissue sampling.
Purpose of the Study:
- To describe the utility and safety of CT guidance for biopsy of diverse skeletal lesions.
- To evaluate the application of CT guidance in spinal and appendicular skeletal biopsies.
- To assess the effectiveness of CT-guided biopsy in a patient cohort with skeletal abnormalities.
Main Methods:
- A retrospective analysis of 46 patients undergoing CT-guided skeletal biopsies.
- Procedures included skinny needle aspirations (18 or 22 gauge) and trephine core biopsies.
- Biopsy sites encompassed thoracic spine, lumbosacral spine, bony pelvis, ribs, and long bones.
Main Results:
- CT guidance facilitated accurate needle placement within skeletal lesions.
- The technique was applied to various spinal and extraspinal bone locations.
- Physicians performing CT-guided procedures received minimal ionizing radiation due to precise visualization.
Conclusions:
- CT guidance is a valuable and safe tool for skeletal lesion biopsy.
- The use of fast CT scanners enhances the feasibility of these procedures.
- CT-guided biopsy offers precise targeting and reduced radiation exposure in skeletal interventions.
More Related Videos
07:10A Sectioning, Coring, and Image Processing Guide for High-Throughput Cortical Bone Sample Procurement and Analysis for Synchrotron Micro-CT
Published on: June 12, 2020
04:20Practical Considerations for the Design, Execution, and Interpretation of Studies Involving Whole-Bone Bending Tests of Rodent Bones
Published on: September 1, 2023
Related Concept Videos
Electron Microscope Tomography and Single-particle Reconstruction
Electron Tomography
Electron tomography can be performed either in TEM or STEM (scanning transmission...
Computed Tomography
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...