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Patterns of Adherence to Secondary Prevention Measures Among Chinese Patients With Coronary Artery Disease: A
Insights
Patient adherence to coronary artery disease (CAD) secondary prevention changes over time. Understanding these adherence trajectories and their predictors is key for improving patient outcomes.
Area of Science:
- Cardiology
- Health Services Research
- Behavioral Science
Background:
- Adherence to secondary prevention measures is crucial for patients with coronary artery disease (CAD).
- Patient adherence behaviors are dynamic and can change significantly over time.
- Understanding these changes is vital for improving patient prognosis and long-term outcomes.
Purpose of the Study:
- To identify distinct adherence trajectories for medication-taking and heart-healthy lifestyle among CAD patients.
- To determine the predictors associated with these identified adherence trajectories.
- To inform targeted interventions for enhancing secondary prevention adherence in CAD.
Main Methods:
- Longitudinal study of 698 patients with CAD post-percutaneous coronary intervention in China.
- Group-based trajectory models were used to analyze adherence patterns over 1 year.
- Multinomial logistic regression identified predictors including demographics, disease knowledge, self-efficacy, and health literacy.
Main Results:
- Four medication-taking adherence trajectories were identified: sustained adherence (39.9%), increasing-decreasing (23.1%), increasing (23.4%), and nonadherence (13.6%).
- Three heart-healthy lifestyle adherence trajectories were found: sustained adherence (59.7%), increasing (28.3%), and nonadherence (12.0%).
- Predictors varied, with marriage linked to sustained medication adherence, and higher health literacy to sustained lifestyle adherence. Lower disease knowledge and absence of coronary stents were associated with lower adherence.
Conclusions:
- Adherence to secondary prevention in Chinese CAD patients follows diverse patterns.
- Healthcare providers should develop tailored support strategies.
- Interventions must consider individual factors like disease knowledge, self-efficacy, and health literacy to improve adherence.
Background:
Adherence to secondary prevention measures among patients with coronary artery disease (CAD) affects patient prognosis, whereas patients' adherence behaviors change over time.
Objectives:
The aims of this study were to identify adherence trajectories to secondary prevention measures including medication-taking and a heart-healthy lifestyle and to estimate predictors of adherence trajectories among patients with CAD.
Methods:
This longitudinal study enrolled 698 patients with CAD who received a percutaneous coronary intervention in China. Demographics, clinical characteristics, adherence to secondary prevention measures, and patient-related factors including disease knowledge, self-efficacy, and health literacy were measured during hospitalization. Adherence behaviors were followed at 1, 3, and 6 months, and 1 year after discharge. Group-based trajectory models estimated adherence trajectories, and multinomial logistic regression identified trajectory group predictors.
Results:
Four trajectory groups were identified for medication-taking adherence: sustained adherence (39.9%), increasing and then decreasing adherence (23.1%), increasing adherence (23.4%), and nonadherence (13.6%). The 3 adherence trajectory groups for a heart-healthy lifestyle were sustained adherence (59.7%), increasing adherence (28.3%), and nonadherence (12.0%). Married patients were more likely (odds ratio [OR], 3.42; 95% confidence interval [CI], 1.56-7.52) to have sustained adherence to medication-taking. However, patients with higher disease knowledge were less likely (OR, 0.93; 95% CI, 0.87-0.99) to be adherent. Patients who were not working (OR, 2.25; 95% CI, 1.03-4.92) had higher self-efficacy (OR, 1.21; 95% CI, 1.08-1.37). Those with higher health literacy (OR, 1.18; 95% CI, 1.01-1.38) were more likely to have sustained adherence to a heart-healthy lifestyle. However, patients having no coronary stents (OR, 0.36; 95% CI, 0.19-0.70) were less likely to have done so.
Conclusions:
Trajectories of adherence to secondary prevention measures among mainland Chinese patients with CAD are multipatterned. Healthcare providers should formulate targeted adherence support, which considers the influence of disease knowledge, self-efficacy, and health literacy.
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