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Bioabsorbable System-Related Subcutaneous Swelling After Craniofacial Surgery.
Yoshiaki Sakamoto1, Tomoru Miwa2, Masahiro Toda2
1Department of Plastic and Reconstructive Surgery.
The Journal of Craniofacial Surgery
|July 9, 2021
Summary
Subcutaneous swelling is a complication of bioabsorbable plates used in pediatric cranioplasty. While both poly D-lactic acid/polyglycolic acid and poly D-/L-lactic acid systems can cause swelling, careful follow-up is essential for all patients.
Area of Science:
- Pediatric Surgery
- Biomaterials Science
- Craniofacial Surgery
Background:
- Bioabsorbable systems are widely used for pediatric cranioplasty.
- Subcutaneous swelling is a known complication of bioabsorbable osteosynthesis.
- The comparative incidence of swelling based on different bioabsorbable materials remains unclear.
Purpose of the Study:
- To compare the incidence of subcutaneous swelling associated with different bioabsorbable materials used in pediatric cranioplasty.
- To analyze the occurrence and resolution of subcutaneous swelling in patients undergoing craniosynostosis repair with resorbable systems.
Main Methods:
- Retrospective review of patients undergoing primary cranioplasty for craniosynostosis (2014-2018).
- Analysis of subcutaneous swelling incidences over a 12-month follow-up period.
- Systematic review of published English-language literature on bioabsorbable systems for craniosynostosis since 1995.
Main Results:
- Two common bioabsorbable material groups were identified: poly D-lactic acid/polyglycolic acid and poly D-/L-lactic acid.
- Poly D-lactic acid/polyglycolic acid systems showed 0%-4.2% swelling incidence (3-9 months follow-up).
- Poly D-/L-lactic acid systems showed 5%-16.7% swelling incidence (6-12 months follow-up); all resolved spontaneously.
Conclusions:
- Determining the definitively superior material for reducing swelling was challenging due to study variations.
- Subcutaneous swelling is an inherent risk with all investigated resorbable systems.
- Preoperative patient counseling and diligent follow-up are crucial for managing this complication.

