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Related Experiment Videos

Erythrocyte sedimentation rate in temporal arteritis.

G Branum1, E W Massey, J Rice

  • 1Division of Neurology, Duke University Medical Center, Durham, NC 27710.

Southern Medical Journal
|December 1, 1987
PubMed
Summary

The erythrocyte sedimentation rate (ESR) is typically elevated in temporal arteritis patients. A normal ESR in suspected cases warrants further diagnostic investigation, as it may indicate an alternative diagnosis.

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Area of Science:

  • Rheumatology
  • Internal Medicine
  • Clinical Pathology

Background:

  • The erythrocyte sedimentation rate (ESR) is a common biomarker used in diagnosing temporal arteritis.
  • There is conflicting literature regarding the prevalence of normal ESR in biopsy-proven temporal arteritis cases.

Purpose of the Study:

  • To evaluate the diagnostic utility of ESR in patients with biopsy-proven temporal arteritis.
  • To determine the frequency of normal ESR values in this patient cohort.

Main Methods:

  • A retrospective analysis of 62 patients with biopsy-proven temporal arteritis.
  • ESR levels were assessed in both untreated and treated patient groups.

Main Results:

  • All 54 untreated patients exhibited an elevated ESR.

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  • Six out of eight treated patients also presented with elevated ESR levels.
  • A normal ESR was observed in a minority of treated patients.

    • Conclusions:

    • An elevated ESR is highly prevalent in biopsy-proven temporal arteritis, particularly in untreated individuals.
    • A normal ESR in a patient with suspected temporal arteritis should raise suspicion for alternative diagnoses.
    • ESR remains a valuable, though not infallible, diagnostic marker for temporal arteritis.