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Shoulder Injury after Vaccination: A Systematic Review
1Departamento de Cirurgia Ortopédica, Icahn School of Medicine at Mount Sinai, Nova York, Nova York, Estados Unidos.
Revista Brasileira De Ortopedia
|July 9, 2021
Summary
Shoulder Injury Related to Vaccine Administration (SIRVA) can occur after routine vaccinations, often presenting as pain and limited motion. Most cases improve with treatment, though some require surgery or result in nerve injury.
Area of Science:
- Orthopedics
- Immunology
- Public Health
Background:
- Adverse reactions to vaccines are rare, but shoulder injuries have been reported.
- Shoulder Injury Related to Vaccine Administration (SIRVA) encompasses bursitis, pain, and reduced range of motion.
- These injuries can occur after routine vaccine administrations.
Purpose of the Study:
- To systematically review published literature on SIRVA.
- To identify common symptoms, treatments, and outcomes associated with SIRVA.
Main Methods:
- A systematic literature review was conducted.
- Twenty-seven papers detailing SIRVA cases were identified and analyzed.
Main Results:
- Influenza vaccines were most commonly implicated.
- Symptoms typically included rapid onset pain (≤48 hours) and loss of shoulder range of motion.
- Physical therapy, corticosteroid injections, and anti-inflammatory medications were common treatments, with surgery needed in some cases.
Conclusions:
- Most SIRVA cases show improved pain and function with treatment, except when nerve injury occurs.
- Potential causes include needle length, overpenetration, and immune responses.
- A definitive diagnostic test for SIRVA is currently lacking.

