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Related Concept Videos

Other Disorders of Digestive System01:30

Other Disorders of Digestive System

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The gastrointestinal tract is susceptible to various disorders. If the lower esophageal sphincter is damaged, stomach acid can flow back into the esophagus, causing irritation and inflammation of the lining. This condition is called gastroesophageal reflux disease (known as heartburn) and may cause chest pain and difficulty swallowing. In the stomach, prolonged use of nonsteroidal anti-inflammatory drugs like aspirin, chronic alcohol consumption, bacterial infections such as Helicobacter...
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What is Monogastric Digestion?01:50

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The human body contains a monogastric digestive system. In a monogastric digestive system, the stomach only contains one chamber in which it digests food. Several other animal species also have monogastric digestive systems, including pigs, horses, dogs, and birds. This chapter, however, focuses on the human digestive system.
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Major Organs of the Digestive System01:19

Major Organs of the Digestive System

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The digestive system is responsible for the ingestion of food, secretion of enzymes, mixing and digesting food, absorption of the nutrients and defecation. The human digestive system consists of two major parts: the gastrointestinal tract and the accessory digestive organs.
Gastrointestinal tract:
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Irritable Bowel Syndrome I: Introduction01:17

Irritable Bowel Syndrome I: Introduction

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Irritable Bowel Syndrome (IBS) is characterized by functional disturbances in the gastrointestinal system, presenting a cluster of symptoms without evident structural or biochemical abnormalities. It primarily affects the large intestine and may cause abdominal pain, bloating, excessive gas, diarrhea, constipation, or both.
IBS is a chronic condition that can persist over a long period or recur frequently.
The pathogenesis of IBS involves a complex interplay of the following factors:
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Regulation of the Digestive System01:25

Regulation of the Digestive System

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Digestive activity regulation hinges on three primary components. Activation is prompted by a multitude of mechanical and chemical indicators, primarily detected by receptors within the stomach and intestines' walls. These receptors predominantly respond to factors such as mechanical stretching of the organ walls, changes in pH and osmolarity, and the presence of digesting materials and their by-products.
The effectors in this regulation system are glands and smooth muscles. Activation of...
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Anatomy of the Gastrointestinal System01:26

Anatomy of the Gastrointestinal System

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The human digestive system is an intricate and essential network for nutrient absorption and waste elimination. It encompasses the gastrointestinal (GI) tract and several accessory organs.
Here's a detailed walkthrough of this complex system:
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Related Experiment Video

Updated: Oct 29, 2025

Author Spotlight: Exploring the Mysteries of Sichuan's Herbal Medicine in Chinese Medicine Research
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COVID-19 and its effects on the digestive system.

Ting-Ting Cao1, Gu-Qin Zhang2, Emily Pellegrini3

  • 1Department of Gastroenterology, Zhongnan Hospital of Wuhan University, Wuhan 430071, Hubei Province, China.

World Journal of Gastroenterology
|July 9, 2021
PubMed
Summary

Coronavirus disease 2019 (COVID-19), caused by SARS-CoV-2, frequently impacts the digestive system, leading to severe illness. Understanding these gastrointestinal symptoms is crucial for diagnosis and patient outcomes.

Keywords:
COVID-19Digestive systemEndoscopyInflammatory bowel diseaseLiver functionMechanisms

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Area of Science:

  • Gastroenterology
  • Infectious Diseases
  • Virology

Background:

  • Coronavirus disease 2019 (COVID-19) is caused by SARS-CoV-2, typically presenting with respiratory symptoms.
  • SARS-CoV-2 can affect organs expressing angiotensin-converting enzyme 2, including the digestive system.
  • Gastrointestinal manifestations of COVID-19 are associated with increased disease severity and mortality.

Purpose of the Study:

  • To summarize digestive system symptoms in COVID-19 patients.
  • To discuss the fecal-oral transmission route of SARS-CoV-2.
  • To review COVID-19 in inflammatory bowel disease patients and endoscopy precautions.

Main Methods:

  • Literature review and synthesis of current research on COVID-19 and the digestive system.
  • Analysis of clinical data regarding gastrointestinal symptoms and disease progression.
  • Examination of transmission dynamics and infection control measures.

Main Results:

  • Digestive symptoms like anorexia, nausea, vomiting, diarrhea, and liver damage are common in COVID-19.
  • Gastrointestinal involvement correlates with a higher risk of severe illness, poorer prognosis, and mortality.
  • Fecal-oral transmission of SARS-CoV-2 is a significant consideration.

Conclusions:

  • Recognizing digestive abnormalities in COVID-19 is vital for clinical diagnosis and management.
  • Attention to gastrointestinal symptoms aids in patient treatment and epidemic control.
  • Specific considerations are needed for inflammatory bowel disease patients and during endoscopic procedures.