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Updated: Oct 29, 2025

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Published on: June 5, 2021
SARS-CoV-2 Infection Inducing Immune Thrombocytopenic Purpura: Case Series
Nancy Guirguis1, Tyler Rehman1, Yara Shams1
1Advocate Christ Medical Center Internal Medicine Residency, University of Illinois at Chicago, Oak Lawn, IL.
Abstract:
Background: Immune thrombocytopenic purpura (ITP) refers to immune-mediated destruction of platelets. Viral infections have been proposed as an etiology of ITP; antibodies developed in response to infection may cross-react with normal platelets and result in their destruction. Case Series: We report 2 cases in which coronavirus disease 2019 (COVID-19) likely induced severe ITP. Conclusion: ITP may also play a role in the thrombocytopenia observed in some patients with COVID-19. ITP in this patient population may be more prevalent than currently documented.
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