Related Experiment Video
Updated: Oct 29, 2025

Novel and Innovative Hybrid Technique for Type A Aortic Dissection
Published on: March 28, 2025
Acquired Gerbode Defect in a Patient With Infective Endocarditis of Bicuspid Aortic Valve
Mohammed Mahdi1, Muhammet Ozer1, Bipinpreet Nagra2
1Internal Medicine, Capital Health Regional Medical Center, Trenton, USA.
Insights
Aortic valve abscess, a severe infective endocarditis complication, can be missed by initial echocardiography. This case highlights a Streptococcus agalactiae infection with abscess and Gerbode defect mimicking tricuspid valve vegetation.
Area of Science:
- Cardiology
- Infectious Diseases
- Medical Imaging
Background:
- Infective endocarditis (IE) is a serious infection affecting heart valves.
- Aortic valve abscess is a life-threatening complication of IE.
- Transthoracic echocardiography (TTE) is the first-line imaging for suspected IE, but has limitations in detecting subtle cardiac complications.
Observation:
- This case involves a bicuspid aortic valve infected by Streptococcus agalactiae.
- The patient developed an aortic valve abscess and an acquired Gerbode defect.
- Initial transthoracic echocardiography revealed findings suggestive of a tricuspid valve vegetation.
Findings:
- The aortic valve abscess and Gerbode defect were confirmed as complications of infective endocarditis.
- Streptococcus agalactiae was identified as the causative pathogen.
- Transthoracic echocardiography findings were misleading, mimicking a different cardiac anomaly.
Implications:
- Transesophageal echocardiography (TEE) is crucial for accurate diagnosis when TTE is inconclusive or clinical suspicion is high.
- Early and accurate diagnosis of aortic valve abscess and associated defects is vital for timely intervention.
- This case underscores the importance of considering advanced imaging in complex IE cases, especially with atypical presentations.
Abstract:
Aortic valve abscess is a fatal complication of infective endocarditis. Transthoracic echocardiography is the initial imaging obtained in suspected infective endocarditis. However, its accuracy in detecting cardiac complications remains low, thus should be followed by transesophageal echocardiography if the clinical situation permits. Here, we present a case of a bicuspid aortic valve infective endocarditis caused by Streptococcus agalactiae and complicated with aortic valve abscess and acquired Gerbode defect, which appeared as a tricuspid valve vegetation on transthoracic echocardiography.
Related Concept Videos
Endocarditis I: Introduction
Aortic Regurgitation I: Introduction
Rheumatic Heart Disease I: Introduction
Endocarditis II: Clinical Features of Infective Endocarditis
Aortic Regurgitation II: Clinical Features and Diagnostic Tests
Endocarditis III: Medical Management

