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Cell Polarization by Rho Proteins

Cell Polarization by Rho Proteins

Cell polarity is the asymmetric distribution of cellular and membrane components, making one side of the cell different from the other. This polarity is essential to many processes such as embryogenesis, axon migration, glucose transport across epithelial cells, and directional cell migration. A migrating cell responds to intracellular or extracellular signals via molecular cascades that reorganize the actin cytoskeleton to establish this polarity. In these cells, the Rho family proteins Cdc42,...

Polarity of the Cytoskeleton

Polarity of the Cytoskeleton

The intrinsic polarity of cells can be primarily attributed to two factors- i) the asymmetric accumulation of mobile components such are regulatory molecules and subcellular components across the cell and ii) the orientation of polar cytoskeletal filaments that make up the cytoskeletal networks, specifically microfilaments, and microtubules arranged along the axis of polarity. Interactions between the cytoskeletal filaments are crucial for the establishment and maintenance of the polar nature...

Cytoskeletal Coordination in Cell Migration

Cytoskeletal Coordination in Cell Migration

A migrating cell changes its shape during the cyclic events of attachment and detachment from the substratum and repositions the cell organelles correspondingly. These complex events are orchestrated by the dynamic cytoskeletal network comprising actin filaments, intermediate filaments, and microtubules. Cytoskeletal crosstalk — the direct and indirect communication between the different components — is crucial for this coordination. Direct communication involves various linker...

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Related Experiment Video

Updated: Oct 29, 2025

In Vitro Reconstitution of Spatial Cell Contact Patterns with Isolated Caenorhabditis elegans Embryo Blastomeres and Adhesive Polystyrene Beads

In Vitro Reconstitution of Spatial Cell Contact Patterns with Isolated Caenorhabditis elegans Embryo Blastomeres and Adhesive Polystyrene Beads

Published on: November 26, 2019

Corrigendum: A Cell Adhesion-Based Reconstitution Method for Studying Cell Polarity.

Christopher A Johnston¹

¹Department of Biology, University of New Mexico, Albuquerque, NM, United States.

Frontiers in Cell and Developmental Biology

|July 9, 2021

Summary

This summary is machine-generated.

This study corrects a previously published article DOI. The correction ensures accurate citation and referencing for future research in the field.

Keywords:

cell polarity mitosis neuroblast reconstitution spindle orientation

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Last Updated: Oct 29, 2025

In Vitro Reconstitution of Spatial Cell Contact Patterns with Isolated Caenorhabditis elegans Embryo Blastomeres and Adhesive Polystyrene Beads

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Rapid and Robust Analysis of Cellular and Molecular Polarization Induced by Chemokine Signaling

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Area of Science:

Cellular Biology
Molecular Mechanisms

Context:

Correction of a previously published article DOI.
Ensuring accurate scientific record-keeping.

Purpose:

To amend the Digital Object Identifier (DOI) for a specific publication.
To maintain the integrity of scientific literature.

Summary:

The article DOI 10.3389/fcell.2020.598492 has been corrected.
This ensures proper attribution and accessibility of the research.

Impact:

Facilitates correct citation and referencing.
Supports the reliability of scientific databases and literature searches.