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Association between mitral annulus calcification and subtypes of heart failure rehospitalization

Yuta Kato1, Tadaaki Arimura2, Yuhei Shiga2

  • 1Department of Cardiology, Fukuoka University School of Medicine, Fukuoka, Japan. y.katoh0119@gmail.com.

Cardiology Journal
|July 9, 2021
PubMed

Insights

Mitral annulus calcification (MAC) is linked to higher rates of heart failure with preserved ejection fraction (HFpEF) rehospitalization. This finding suggests MAC may impact left ventricular diastolic function.

Area of Science:

  • Cardiology
  • Cardiovascular Diseases
  • Echocardiography

Background:

  • Mitral annulus calcification (MAC) is associated with cardiovascular diseases.
  • The specific relationship between MAC and different heart failure (HF) categories remains unclear.
  • Understanding these associations is crucial for patient management.

Purpose of the Study:

  • To investigate the association between MAC and rehospitalization for three HF types: HF with preserved ejection fraction (HFpEF), HF with mid-range EF (HFmrEF), and HF with reduced EF (HFrEF).

Main Methods:

  • Consecutive patients admitted for congestive HF between April 2014 and March 2018 were enrolled.
  • Echocardiography was performed on all patients.
  • Cox proportional-hazards models were used for analysis, adjusting for age, gender, and hypertension.

Main Results:

  • Of 353 patients, 40 (11.3%) had MAC.
  • Patients with MAC showed a significantly higher incidence of HFpEF rehospitalization (p < 0.001).
  • No significant differences in HFmrEF or HFrEF rehospitalization rates were observed between MAC and non-MAC groups.

Conclusions:

  • Mitral annulus calcification is associated with an increased risk of HFpEF rehospitalization.
  • MAC may contribute to left ventricular diastolic dysfunction.
Abstract

Keywords:
heart failureheart failure with preserved ejection fractionmitral annulus calcification

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