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[Functional and morphological changes in the stomach in irradiation of the para-aortic region]
S A Beyer-Enke1, R Gladisch, M Heine
1Institut für Klinische Radiologie, Klinikum der Stadt Mannheim der Universität Heidelberg.
Abstract:
Six assays were conducted in order to determine some functional and morphological parameters of the gastric mucosa in patients who underwent Co60 irradiations of the para-aortic area. Slight as well as marked morphological alterations were observed whereas the functional alterations were found to be marked in all cases. Basal gastric secretion and serum gastrin level showed a continuous reduction, however, in case of severe gastritis the stimulated secretion was increased. A possible correlation with increased tissue histamine levels is discussed.