Enhanced Recovery After Gastrointestinal Surgery (ERAS) in Pediatric Patients: a Systematic Review and Meta-analysis

Salvatore Arena1, Donatella Di Fabrizio2, Pietro Impellizzeri2

  • 1Department of Human Pathology of Adult and Childhood "Gaetano Barresi", Unit of Pediatric Surgery, University of Messina, Messina, Italy. salarena@unime.it.

Insights

The Enhanced Recovery After Surgery (ERAS) protocol is safe for pediatric gastrointestinal surgery. It reduces hospital stay, speeds recovery, and lowers costs without increasing complications or readmissions.

Area of Science:

  • Pediatric Surgery
  • Surgical Protocols
  • Evidence-Based Medicine

Background:

  • The Enhanced Recovery After Surgery (ERAS) protocol aims to optimize patient recovery pathways.
  • Its application in pediatric gastrointestinal surgery requires systematic evaluation.

Purpose of the Study:

  • To systematically review the literature on the ERAS protocol in pediatric gastrointestinal surgery.
  • To assess the safety, feasibility, and impact of ERAS on patient outcomes.

Main Methods:

  • A literature search identified studies comparing ERAS and traditional protocols in pediatric gastrointestinal surgery.
  • Data on complications, readmission, length of stay, fluid management, opioid use, and costs were analyzed.

Main Results:

  • Eight studies with 943 patients were included.
  • No significant differences in complications or 30-day readmission rates were found.
  • ERAS significantly reduced length of stay, intraoperative fluid volume, post-operative opioid use, and costs.

Conclusions:

  • The ERAS protocol is safe and feasible for pediatric gastrointestinal surgery.
  • It improves recovery of gastrointestinal function and reduces perioperative resource utilization.
  • ERAS offers significant benefits in terms of patient recovery and healthcare costs.
Abstract

Related Concept Videos

Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy01:26

Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy

Sigmoidoscopy and laparoscopy are distinct medical procedures that enable physicians to internally inspect different parts of the GI tract. Although they serve different purposes, each is essential for diagnosing and, in some cases, treating various medical conditions.
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
242
Inflammatory Bowel Disease V: Surgical Management01:21

Inflammatory Bowel Disease V: Surgical Management

Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
267
Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption01:23

Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption

Understanding the physiological differences in the pediatric population is crucial for effective pharmacotherapy. Neonates, infants, and children exhibit significant variations in gastric pH, gastric emptying time, intestinal transit time, and biliary function. These variations profoundly affect oral drug absorption, necessitating a nuanced approach to pediatric dosing.Neonates present with a unique physiological profile, having a gastric pH greater than 4 and faster and more irregular gastric...
45
Pharmacokinetics in Pediatric Patients: Drug Metabolism01:24

Pharmacokinetics in Pediatric Patients: Drug Metabolism

In pediatric care, understanding the nuances of hepatic drug metabolism is crucial, as it significantly differs from that of adults. This divergence is primarily due to the developmental stage of drug-metabolizing enzymes, which affects how medications are processed in the body. In neonates, for instance, the activity of Phase I enzymes—critical for the initial breakdown of drugs—is markedly reduced, functioning at just 20–40% of the levels seen in adults. This reduction poses...
47
Peptic Ulcer Disease V: Surgical Management and Nursing Care01:25

Peptic Ulcer Disease V: Surgical Management and Nursing Care

Surgical management and nursing care are crucial in treating Peptic Ulcer Disease (PUD). Here is an organized and enhanced overview of the surgical interventions and the associated nursing care for PUD:
Surgical Interventions for Peptic Ulcer Disease
530
Appendicitis-II: Diagnostic Studies and Management01:29

Appendicitis-II: Diagnostic Studies and Management

Diagnosing and managing appendicitis requires a structured and comprehensive approach that spans from initial assessment to postoperative care. Here is an overview of the process:
Diagnosing Appendicitis
It requires a multifaceted approach, starting with a detailed physical examination to pinpoint the location and nature of the pain and identify any associated symptoms. Laboratory tests play a crucial role. A complete Blood Count (CBC) typically reveals leukocytosis (an increased number of...
197