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Spinal Cord Stimulation for Painful Diabetic Peripheral Neuropathy: A Systematic Review
Josianna V Henson1, Narayana C Varhabhatla1, Zvonimir Bebic1
1Department of Anesthesiology, University of Colorado School of Medicine, Aurora, CO, 80045, USA.
Pain and Therapy
|July 10, 2021
Summary
Spinal cord stimulation offers a safe and effective treatment for painful diabetic neuropathy, providing relief from pain and disability. Further research is recommended to confirm these findings.
Area of Science:
- Neurology
- Pain Management
- Medical Devices
Background:
- Painful diabetic neuropathy is a prevalent condition causing significant pain and disability.
- Current treatments like medications and TENS units have variable efficacy and tolerability issues.
- Spinal cord stimulation (SCS) is an emerging alternative for managing lower extremity neuropathic pain.
Purpose of the Study:
- To systematically review the safety and effectiveness of spinal cord stimulation for treating painful diabetic neuropathy.
- To evaluate the existing evidence on SCS as a therapeutic option for this condition.
Main Methods:
- A systematic literature review was conducted.
- A comprehensive search identified 14 prospective studies.
- Evidence quality was assessed to determine the reliability of findings.
Main Results:
- The review found moderate-quality evidence supporting the safety and efficacy of SCS for painful diabetic neuropathy.
- Analysis indicates SCS can be a viable treatment option for patients with this condition.
Conclusions:
- Spinal cord stimulation demonstrates moderate evidence of safety and efficacy for painful diabetic neuropathy.
- High-quality research, including large-scale randomized controlled trials, is necessary to further validate these results.

