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Quality of life in children with atopic dermatitis: A one-year prospective cohort study
Tatjana Gazibara1, Vesna Reljic2, Slavenka Jankovic1
1Institute of Epidemiology, Faculty of Medicine, University of Belgrade, Belgrade, Serbia.
Insights
Children with mild atopic dermatitis experienced improved quality of life over one year. Lower SCORAD scores at the start and greater improvement predicted better outcomes in children's atopic dermatitis quality of life.
Area of Science:
- Pediatric Dermatology
- Quality of Life Research
- Chronic Disease Management
Background:
- Limited data exists on quality of life (QoL) trends in children with atopic dermatitis (AD) over time.
- Atopic dermatitis significantly impacts a child's daily life and well-being.
Purpose of the Study:
- To evaluate factors influencing the quality of life in children with atopic dermatitis after a year.
- To identify predictors of enhanced atopic dermatitis-related quality of life over a 12-month period.
Main Methods:
- A cohort of 98 children with atopic dermatitis was assessed using SCORing Atopic Dermatitis (SCORAD), Children's Dermatology Life Quality Index (CDLQI), and Infants' Dermatitis Quality of Life Index (IDLQI).
- Quality of life impairment was categorized as mild, moderate, or severe.
- Eighty children completed a one-year follow-up assessment.
Main Results:
- Children with mild atopic dermatitis showed improvements in QoL (CDLQI/IDLQI) after one year.
- No significant QoL improvements were noted in children with moderate to severe atopic dermatitis.
- Lower initial SCORAD scores and greater SCORAD improvement correlated with better QoL at follow-up.
Conclusions:
- Children with less severe atopic dermatitis demonstrated a higher likelihood of improved QoL.
- Initial and improved SCORAD scores are key indicators for predicting better quality of life in pediatric atopic dermatitis patients.
- Findings suggest that managing AD severity is crucial for enhancing children's quality of life.
Background:
Literature on the quality of life trends across time in children with atopic dermatitis are scarce.
Aims:
To assess factors associated with quality of life of children with atopic dermatitis after a one-year follow-up and to examine the factors contributing to greater improvement in the atopic dermatitis-related quality of life over one year.
Methods:
Our cohort consisted of 98 children who were treated for atopic dermatitis at the clinic of dermatovenereology. Data collection included atopic dermatitis scoring using the SCORing Atopic Dermatitis (SCORAD) index, Children's Dermatology Life Quality Index (CDLQI) for children aged > four years and Infants' Dermatitis Quality of Life Index (IDLQI) for children aged 0-4 years. Categorization of the impairment of quality of life score due to atopic dermatitis was as follows: mild (score from 0 to 6), moderate (score from 7 to 12) and severe (score from 13 to 30). The cohort was followed for one year after which a total of 80 children were reassessed.
Results:
Improvements of both CDLQI and IDLQI were observed in children whose impairment of quality of life due to atopic dermatitis after one year was 'mild'. This was not observed in children whose atopic dermatitis caused either 'moderate' or 'severe impairment' of their quality of life. Adjusted analysis showed that lower initial SCORAD and greater improvement in SCORAD after the one-year follow-up were associated with a better quality of life at follow-up.
Limitations:
The size of our cohort was relatively small. Study participants were recruited from the largest urban and medical referral center in Serbia. Persons from suburban or rural regions may have had different perceptions of atopic dermatitis-related quality of life.
Conclusion:
Children with less severe atopic dermatitis were more likely to improve their atopic dermatitis-related quality of life. Lower SCORAD was associated with both better quality of life initially and greater improvement in quality of life after one year of follow-up.
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