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Updated: Oct 29, 2025

A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment
Published on: January 11, 2020
Design, implement, and diffuse scalable and sustainable solutions for dementia care
Malaz Boustani1,2,3, Jürgen Unützer4, Luci K Leykum5,6
1Department of Medicine, Indiana University, Center for Health Innovation and Implementation Science, Indianapolis, Indiana, USA.
Innovations for Alzheimer disease and related dementias (ADRD) face implementation challenges, leading to suboptimal care. Addressing limited demand, engagement, scalability, and contextual adaptation is crucial for improving ADRD services.
Area of Science:
- Gerontology
- Health Services Research
- Human-Centered Design
Background:
- Alzheimer disease and related dementias (ADRD) pose significant burdens.
- Current innovations struggle with implementation, diffusion, and scalability.
- Suboptimal care and harm result from these implementation challenges.
Purpose of the Study:
- Identify factors limiting the implementation and diffusion of evidence-based ADRD interventions.
- Highlight the need for improved strategies to scale and sustain ADRD care services.
- Emphasize the importance of human-centered design in addressing ADRD care.
Main Methods:
- Expert identification of key barriers to implementation and diffusion.
- Analysis of factors affecting the adoption of ADRD interventions.
- Review of existing evidence on scalability and sustainability.
Main Results:
- Four primary factors hinder ADRD innovation adoption: limited market demand, insufficient stakeholder engagement, lack of scalability evidence, and contextual transfer difficulties.
- These barriers result in suboptimal care for individuals with ADRD and their caregivers.
Conclusions:
- New investments in human-centered design, implementation science, and diffusion science are essential.
- These investments are critical for achieving the goals of the National Plan to Address Alzheimer's Disease.
- Addressing the identified factors will improve the delivery of effective ADRD services.
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