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Updated: Oct 29, 2025

Whole Genome Sequencing of Candida glabrata for Detection of Markers of Antifungal Drug Resistance
Published on: December 28, 2017
Candida Bloodstream Infections: Changes in Epidemiology and Increase in Drug Resistance
Fleischer Cn Kotey1,2, Nicholas Tkd Dayie1, Patience B Tetteh-Uarcoo1
1Department of Medical Microbiology, University of Ghana Medical School, Korle Bu, Accra, Ghana.
Abstract:
The literature on bloodstream infections (BSIs) have predominantly been biased towards bacteria, given their superior clinical significance in comparison with the other types of microorganisms. Fungal pathogens have epidemiologically received relatively less attention, although they constitute an important proportion of BSI aetiologies. In this review, the authors discuss the clinical relevance of fungal BSIs in the context of Candida species, as well as treatment options for the infections, emphasizing the compelling need to develop newer antifungals and strengthen antimicrobial stewardship programmes in the wake of the rapid spread of antifungal resistance.
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