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Multiple Anthelmintic Resistance at a Goat Farm in Slovakia
M Babják1, A Königová1, M Várady1
1Institute of Parasitology, Slovak Academy of Sciences, Hlinkova 3, 040 01 Košice, Slovak Republic.
Helminthologia
|July 12, 2021
Summary
Parasite resistance to common goat dewormers is rising in Europe. Studies show ivermectin and benzimidazole have reduced efficacy, while levamisole remains effective against goat parasites.
Area of Science:
- Veterinary Parasitology
- Animal Health
- Drug Resistance
Background:
- Anthelmintic resistance in small ruminants is a growing concern in European livestock.
- Parasitic infections significantly impact goat productivity and farm economics.
Purpose of the Study:
- To investigate anthelmintic resistance in goats on a Slovakian farm.
- To evaluate the efficacy of ivermectin, benzimidazole, and levamisole against gastrointestinal parasites.
Main Methods:
- Conducted an in vivo faecal egg count reduction test (FECRT).
- Performed an in vitro larval development test (LDT).
- Assessed minimum inhibitory concentrations (MIC) and LD50 for key anthelmintics.
Main Results:
- Ivermectin showed the lowest efficacy (60%) via FECRT, with MIC exceeding thresholds.
- Benzimidazole efficacy ranged from 80.3-86.5%, indicating potential resistance.
- Levamisole demonstrated high efficacy (94%) and susceptibility in LDT.
Conclusions:
- Evidence of resistance to ivermectin and potential resistance to benzimidazoles in the studied goat population.
- Levamisole remains an effective option for controlling goat parasites in this region.
- Continued monitoring of anthelmintic resistance is crucial for sustainable parasite management.
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