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Updated: Oct 29, 2025

Intracellular Phosphoflow Cytometry of Acute Myeloid Leukemia Patient-Derived Xenotransplants
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Intracellular Phosphoflow Cytometry of Acute Myeloid Leukemia Patient-Derived Xenotransplants

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Glutamate-cysteine ligase catalytic subunit as a therapeutic target in acute myeloid leukemia and solid tumors

Chiou-Hong Lin1, John P Vu1, Chen-Yen Yang1

  • 1AbbVie Oncology Discovery Sunnyvale, CA 94085, USA.

American Journal of Cancer Research
|July 12, 2021
PubMed

Keywords:
Acute myeloid leukemia (AML)CRISPRglutamate-cysteine ligase catalytic subunit (GCLC)glutathione metabolic enzymesynthetic lethality

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