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[Histomorphologic prognostic factors in stage I endometrial cancers]
U Köhler1, K Bilek, M Rosenkranz
1Klinik für Gynäkologie und Geburtshilfe, Bereichs Medizin der Karl-Marx-Universität Leipzig.
Abstract:
The prognostic significance of qualitative and quantitative morphological tumour characteristics for endometrial carcinoma of stage I (FIGO) is to be ascertained from the available 230 operation specimens from 1976 to 1983 (inclusive). The fundamental objective is to design a standardized and reliably reproducible histological technique. By utilizing a multi-dimensional statistical comparison (multiple regression analysis), the maximal relative extent of the endometrial invasion as a determinant prognostic feature shall also be ascertained. Furthermore, the degree of differentiation (Grading) and tumour type (Typing) influence the survival rate whereas the maximal superficial extension of the carcinoma has no significant prognostic importance.