Related Experiment Video
Updated: Oct 29, 2025

Handheld Metal Detector Screening for Metallic Foreign Body Ingestion in Children
Published on: September 11, 2018
A systematic review on pediatric medication errors by parents or caregivers at home
Adriana Lopez-Pineda1,2, Javier Gonzalez de Dios3,4,5, Mercedes Guilabert Mora6
1Clinical Medicine Department, Miguel Hernández University, San Juan de Alicante, Spain.
Insights
Pediatric medication errors (MEs) at home occur frequently, ranging from 30% to 80%. Caregiver factors and polypharmacy increase risks, but improved dosing tools and education can reduce these errors.
Area of Science:
- Pediatric Patient Safety
- Medication Error Research
- Home Healthcare
Background:
- Medication errors (MEs) are a significant concern, potentially leading to severe outcomes like hospitalization or death.
- Most pediatric medications are administered by parents or caregivers in a home setting.
- Understanding home-based pediatric MEs is crucial for enhancing patient safety.
Purpose of the Study:
- To review the literature on the frequency of pediatric MEs by caregivers at home.
- To identify factors associated with pediatric MEs in the home environment.
- To examine pediatric ME reporting systems in outpatient settings.
Main Methods:
- A comprehensive literature search was conducted across Medline, Scopus, Embase, and ScienceDirect databases.
- Original articles and reviews published between 2013 and 2021 were included.
- The search focused on the frequency, associated factors, and reporting systems of pediatric MEs.
Main Results:
- The reported frequency of pediatric MEs at home varied widely, from 30% to 80%.
- Caregiver characteristics and prescriptions involving three or more drugs were identified as risk factors.
- No information was found regarding pediatric ME reporting systems in the outpatient setting.
Conclusions:
- Providing accurate dosing tools and recommending syringes can help reduce pediatric MEs.
- Educational interventions for caregivers are essential for improving medication safety at home.
- Further research is needed to establish effective reporting systems for outpatient pediatric MEs.
Introduction:
Medication errors (MEs) are frequent and, in some cases, can lead to hospitalization, disability, increased healthcare costs or, even, death. Most of pediatric medications are administered by parents or caregivers at home. It is necessary to explore the MEs at home to improve pediatric patient safety.
Areas Covered:
This study aimed to review the current literature on the frequency of pediatric MEs by parents or caregivers at home, their associated factors, and pediatric ME reporting systems. Citable original articles of any type of study design or reviews published from 2013 to 2021 were searched in Medline, Scopus, Embase, and ScienceDirect databases.
Expert Opinion:
The available data about the frequency of pediatric MEs at home varied from 30% to 80%. Current research suggests the risk of making a ME in pediatric patients at home may depend on the characteristics of the caregiver and may increase if a prescription contains ≥3 drugs. Findings conclude that providing dosing tools more closely matched to prescribed dose volumes, recommending the use of syringes as a measurement tool, and educational intervention for caregivers could be useful to reduce MEs. Concerning the reporting systems for pediatric MEs in the outpatient setting, no information was found.
Related Concept Videos
Pharmacokinetics in Pediatric Patients: Drug Metabolism
Pharmacokinetics in Pediatric Patients: Drug Excretion
Drug Dosing: Infants and Children
Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption
Pharmacokinetics in Pediatric Patients: Drug Distribution
Pharmacovigilance
This process, termed pharmacovigilance, aims to detect, evaluate, and minimize harmful effects related to medication use. The data collection for pharmacovigilance depends on spontaneous reporting systems, where healthcare professionals or patients voluntarily report suspected ADRs.
In some cases, there...

