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A single neonatal treatment with methylcholanthrene or benzo(a)pyrene alters microsomal enzyme activity for life
G Csaba1, O Dobozy, S Szeberényi
1Department of Biology, Semmelweis University of Medicine, Budapest, Hungary.
Acta Physiologica Hungarica
|January 1, 1987
Abstract:
A single neonatal exposure to methylcholanthrene or benzo(a)-pyrene altered the hepatic microsomal enzyme activity of rats for a long time. Methylcholanthrene depressed, whereas benzo(a)pyrene enhanced the activity of the microsomal enzyme system. The former had a greater influence on males than on females, whereas the latter acted practically uniformly on both sexes.