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Updated: Oct 29, 2025
Evaluating Cell Death Signaling by Immunofluorescence in a Rat Model of Ischemic Stroke
Published on: January 3, 2025
Mortality rate and biomarker expression within COVID-19 patients who develop acute ischemic stroke: a systematic
Ahmed Yassin1, Ansam Ghzawi2, Abdel-Hameed Al-Mistarehi3
1Division of Neurology, Department of Neurosciences, Faculty of Medicine, Jordan University of Science & Technology, Irbid, Jordan.
Objective:
To describe the mortality difference between acute ischemic stroke (AIS) and non-AIS groups within COVID-19 patients.
Materials & Methods:
We included observational studies through September 2020 that categorized COVID-19 patients into two groups (with and without AIS).
Results:
Eight studies with a total sample size of 19,399 COVID-19 patients were included. The pooled risk difference showed that patients with COVID-19 who developed AIS had significantly higher mortality than those without AIS by a risk difference of 24% (95% CI: 0.10-0.39; p = 0.001). In two studies, the COVID-19+AIS group had significantly higher lymphocytes, procalcitonin and creatinine levels.
Conclusion:
Developing AIS significantly adds to the mortality of COVID-19. Timely interventions to manage those patients are strongly recommended.
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