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Related Concept Videos

Drugs for Treatment of Ulcerative Colitis in IBD01:29

Drugs for Treatment of Ulcerative Colitis in IBD

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Ulcerative colitis is a chronic inflammatory condition primarily affecting the colon and rectum. The primary drugs used in the treatment of ulcerative colitis are aminosalicylates. They exhibit anti-inflammatory and immunosuppressive properties. They modulate inflammatory mediators and inhibit the activity of nuclear factor κB (NF-κB). Aminosalicylates also reduce inflammation by inhibiting prostaglandin and leukotriene production and decreasing neutrophil chemotaxis and superoxide...
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Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy01:30

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Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
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Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
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Inflammatory Bowel Disease IV: Pharmacological Management01:29

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Upon diagnosis, managing Inflammatory Bowel Disease (IBD) involves addressing several crucial aspects. The primary goals include resting the bowel, correcting malnutrition, and providing symptomatic relief. Resting the bowel may consist of medications to reduce inflammation and promote healing. Correcting malnutrition is essential, often requiring dietary adjustments and nutritional supplements. Symptomatic relief aims to ease pain, diarrhea, and other discomforts in IBD.
Pharmacologic...
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Peptic Ulcer Disease IV: Management01:26

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Medical treatment strategies for peptic ulcers encompass various methods. The primary goal of treatment is to diminish gastric acidity and strengthen mucosal defense mechanisms.
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Pharmacological management
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Inflammatory Bowel Disease I: Ulcerative Colitis01:27

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Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
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Chinese Herbal Retention Enema for the Treatment of Ulcerative Colitis
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Adherence improvement in patients with ulcerative colitis: a multidisciplinary consensus document.

Francesc Casellas1, Yago González-Lama2, Daniel Ginard Vicens3

  • 1Digestive Diseases, Hospital Universitari Vall d'Hebron, España.

Revista Espanola De Enfermedades Digestivas
|July 13, 2021
PubMed
Summary

Poor adherence is common in ulcerative colitis (UC) patients. A multidisciplinary committee developed a framework with principles and recommendations to improve patient adherence and management.

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Area of Science:

  • Gastroenterology
  • Patient Adherence Research
  • Clinical Practice Guidelines

Background:

  • Poor adherence is a significant clinical concern in ulcerative colitis (UC) management.
  • Understanding prevalence, contributing factors, and effective interventions is crucial for improving patient outcomes.

Purpose of the Study:

  • To analyze existing evidence on non-adherence in UC patients, including prevalence, associated factors, and interventions.
  • To develop a framework and actionable recommendations for enhancing adherence in UC.

Main Methods:

  • A qualitative approach utilizing a comprehensive literature review of 75 articles from Medline.
  • Quality assessment using the Oxford scale and synthesis of findings by a multidisciplinary committee.
  • Consensus generation through a Delphi process to establish overarching principles and recommendations.

Main Results:

  • Non-adherence rates in UC patients varied widely, from 7% to 72%.
  • Significant variability was observed in methods for assessing adherence, factors, and interventions.
  • Eight overarching principles and six recommendations for managing non-adherence were established with high consensus.

Conclusions:

  • Poor adherence is a prevalent and clinically relevant issue in ulcerative colitis.
  • Healthcare professionals must proactively address adherence challenges.
  • Individualized, patient-centered interventions are essential for improving adherence in UC.