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Updated: Oct 29, 2025

Imaging Denatured Collagen Strands In vivo and Ex vivo via Photo-triggered Hybridization of Caged Collagen Mimetic Peptides
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Peptoid Residues Make Diverse, Hyperstable Collagen Triple-Helices

Julian L Kessler1, Grace Kang1, Zhao Qin2

  • 1Department of Biomedical Engineering, University of Utah, Salt Lake City, Utah 84112, United States.

Journal of the American Chemical Society
|July 13, 2021
PubMed
Summary

N-substituted glycines (N-glys) mimic proline's collagen-like triple-helix structure, enabling diverse, stable collagen mimetic peptides. This discovery offers new avenues for collagen-based therapeutics and biomaterials.

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