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Updated: Oct 29, 2025
14:49
Conducting Respiratory Oscillometry in an Outpatient Setting
Published on: April 8, 2022
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"Reactance inversion" at low frequencies during lung function measurement by impulse oscillometry in children with
Ramiro González Vera1, Alberto Vidal Grell1, Alejandra Mendez Yarur1
1Department of Pediatric Pulmonology, Clínica Las Condes, Santiago, Chile.
Summary
Corrected reactance at 5 Hz (CX5) is common in children with asthma, decreasing with age. This CX5 parameter correlates better than standard reactance (X5) with impulse oscillometry measures for assessing small airway dysfunction.
Area of Science:
- Pediatric Pulmonology
- Respiratory Physiology
- Asthma Research
Background:
- Small airway dysfunction (SAD) is a key feature of asthma.
- Impulse oscillometry (IOS) is used to measure SAD.
- A corrected reactance at 5 Hz (CX5) parameter may offer improved assessment of SAD.
Purpose of the Study:
- To investigate the prevalence of CX5 in asthmatic children.
- To determine the correlation of CX5 with other IOS parameters.
- To compare the utility of CX5 versus standard reactance (X5) in evaluating SAD.
Main Methods:
- A transversal study involving 507 children (3-18 years) using IOS-spirometry.
- Analysis of parameters including R5, AX, Fres, X5, CX5, D5-20, and spirometry.
- Determination of CX5 prevalence by age and correlation analysis with IOS parameters.
Main Results:
- CX5 was prevalent in 83.5% of preschool children, decreasing with age.
- Children with CX5 showed significantly higher R5, AX, D5-20 and lower FEV1.
- CX5 demonstrated a stronger correlation with IOS-spirometry parameters than X5 across all ages.
Conclusions:
- Reactance inversion and CX5 are frequent in asthmatic children.
- The prevalence of CX5 decreases with age.
- CX5 is a more effective IOS parameter than X5 for evaluating SAD in children.
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