Related Experiment Video
Updated: Oct 29, 2025

08:03
Inchworming: A Novel Motor Stereotypy in the BTBR T+ Itpr3tf/J Mouse Model of Autism
Published on: July 5, 2014
11.9K
McKittrick-Wheelock Syndrome: A Case Series
Maureen Elvira P Villanueva1, Mark Augustine S Onglao1, Mayou Martin T Tampo1
1Division of Colorectal Surgery, Philippine General Hospital, University of the Philippines Manila, Manila, Philippines.
Annals of Coloproctology
|July 13, 2021
Summary
McKittrick-Wheelock syndrome, a rare condition with diarrhea, kidney issues, and colorectal tumors, can be fatal if untreated. Surgical tumor removal offers a life-saving treatment, resolving symptoms and improving organ function.
Area of Science:
- Gastroenterology and Nephrology
Background:
- McKittrick-Wheelock syndrome is a rare, life-threatening condition.
- It presents with chronic mucous diarrhea, renal impairment, and giant colorectal tumors, often rectal adenomas.
Observation:
- Three cases of McKittrick-Wheelock syndrome were managed surgically.
- The surgeries were performed at the Philippine General Hospital between August 2018 and May 2019.
Findings:
- Surgical resection of the colorectal tumor led to symptom resolution.
- Renal function improved, and hydroelectrolyte balance was restored post-surgery.
- Sphincter-saving operations were successfully employed.
Implications:
- Early diagnosis and surgical intervention are crucial for managing McKittrick-Wheelock syndrome.
- Surgical resection is an effective treatment, improving patient outcomes.
- Raising awareness of this rare syndrome is vital for timely management.

