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Author Spotlight: Developing a Disposable Dosator for Preclinical Testing of Dry Powder Inhalers in Small Animal Models
Published on: August 18, 2023
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Not so Goody's powder.
Raja Samir Khan1, Sardar Momin Shah-Khan2, Justin Kupec2
1Department of Medicine, West Virginia University, Morgantown, West Virginia, USA rajasamirkhan.aku@gmail.com.
BMJ Case Reports
|July 14, 2021
Summary
Analgesic powders, commonly used by adults, can lead to serious gastrointestinal issues. This case highlights a rare gastrocolic fistula complication from peptic ulcer disease linked to analgesic powder use.
Area of Science:
- Gastroenterology
- Internal Medicine
- Pharmacology
Background:
- Over-the-counter (OTC) analgesic medications are prevalent among American adults.
- Analgesic powders are a common dosage form, with known adverse effects documented in medical literature.
- Peptic ulcer disease is a recognized complication of analgesic use.
Observation:
- A patient presented with upper gastrointestinal bleeding and acute anemia.
- The patient reported consistent use of analgesic powders.
- Diagnostic evaluation revealed a peptic ulcer complicated by a gastrocolic fistula.
Findings:
- Gastrocolic fistula is a previously unreported complication of peptic ulcer disease specifically associated with analgesic powder usage.
- The patient's upper gastrointestinal bleeding and anemia were directly linked to this fistula.
- This case underscores a rare but severe adverse outcome of analgesic powder consumption.
Implications:
- Highlights a novel complication of analgesic powder use, expanding the understanding of potential adverse effects.
- Emphasizes the importance of considering gastrocolic fistula in patients with peptic ulcer disease and a history of analgesic powder consumption.
- Suggests a need for increased awareness among healthcare providers regarding this specific risk associated with analgesic powders.

