Multiresistent Cupriavidus pauculus infection in an immunocompromised elderly patient

Area of Science:

• Microbiology
• Infectious Diseases
• Clinical Medicine

Background:

• Cupriavidus pauculus is an aerobic, gram-negative bacillus found widely in nature.
• While typically avirulent, it can cause severe infections in both immunocompromised and immunocompetent individuals.

Observation:

• An elderly patient presented with septic shock and a urinary tract infection.
• During hospitalization, the patient's condition worsened, with blood cultures positive for Cupriavidus pauculus.

Findings:

• Cupriavidus pauculus infection was identified as the cause of the patient's deteriorating condition.
• The isolated bacteria demonstrated sensitivity only to minocycline.

Implications:

• This case highlights the potential severity of Cupriavidus pauculus infections, even in elderly patients with multiple comorbidities.
• Effective and timely antimicrobial therapy, such as minocycline, is crucial for managing such rare infections.
• The case underscores the importance of considering unusual pathogens in severe sepsis and septic shock presentations.