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Reference values for the cross-sectional area of the normal sciatic nerve using high-resolution ultrasonography
Kunwar Pal Singh1, Prabhjot Singh1, Kamlesh Gupta1
1Radiodiagnosis, SGRD University of Health Sciences, India.
Journal of Ultrasonography
|July 14, 2021
Summary
High-resolution ultrasonography provides reference values for normal sciatic nerve size. Sciatic nerve cross-sectional area correlates with height, weight, and BMI, but not age, aiding in diagnosing nerve conditions.
Area of Science:
- Neurology
- Medical Imaging
- Anatomy
Background:
- High-resolution ultrasonography (HRUS) is a validated diagnostic tool for neurological conditions in adults.
- Its application in evaluating peripheral and spinal nerves is emerging.
Purpose of the Study:
- To establish reference values for the cross-sectional area (CSA) of the normal sciatic nerve using HRUS.
- To investigate the relationship between sciatic nerve CSA and demographic factors (age, gender, height, weight, BMI).
Main Methods:
- HRUS was performed on 200 healthy adult subjects (age > 18) with no history of neuropathy or lower limb trauma.
- Sciatic nerve CSA was measured at two distinct levels (1 cm and 4 cm above bifurcation) in both lower limbs.
Main Results:
- Sciatic nerve CSA showed a positive correlation with height, weight, and body mass index.
- Women exhibited smaller sciatic nerve CSA compared to men at both measurement sites.
- No significant correlation was found between sciatic nerve CSA and subject age.
Conclusions:
- The study established reference values for normal sciatic nerve CSA.
- These reference values are valuable for analyzing pathological nerve conditions using HRUS.

