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Within-Host Phenotypic Evolution and the Population-Level Control of Chronic Viral Infections by Treatment and

Dmitry Gromov1,2, Ethan O Romero-Severson3

  • 1Faculty of Applied Mathematics and Control Processes, Saint Petersburg State University, St. Petersburg 199034, Russia.

Mathematics (Basel, Switzerland)
|July 14, 2021
PubMed
Summary

This study introduces a mathematical framework to understand how viral evolution impacts chronic infection control. It analyzes how viral diversity, contagiousness, and treatment resistance affect public health strategies for managing infections.

Keywords:
basic reproduction numbermathematical modelingmulti-strain infectious diseasessensitivity analysis

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