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Related Concept Videos

Pulmonary Tuberculosis IV01:26

Pulmonary Tuberculosis IV

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Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
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Pulmonary Tuberculosis III01:31

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Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
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Pulmonary Tuberculosis II01:28

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Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
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Pulmonary Tuberculosis V01:28

Pulmonary Tuberculosis V

284
Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
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Pulmonary Tuberculosis I01:29

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434
Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
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Do Pedicle Screws in Concave Apex of Scoliosis Offer Any Advantages?

Asian spine journal·2018
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A Retrospective Study on Endoscopic Surgery for the Treatment of Paravertebral Abscess in Spinal Tuberculosis Patients
03:47

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Can We Extrapolate SINS Score to Evaluate Instability in Spinal Tuberculosis?

Yogesh Kishorkant Pithwa1, Vikrant Sinha Roy1

  • 1FNB Spine Surgery, HOSMAT Hospital and Sattvik Spine & Scoliosis Center, Bengaluru, Karnataka, India.

Global Spine Journal
|July 14, 2021
PubMed
Summary

The Spinal Instability Neoplastic Score (SINS) effectively aids surgical decisions for spinal tuberculosis, improving pain and function. This score helps guide treatment for spinal instability, even in non-neoplastic conditions.

Keywords:
TBfusioninfectioninstabilityspinal instabilityspinal tuberculosisspinespondylitisspondylodiscitistuberculosis

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Area of Science:

  • Orthopedics
  • Neurosurgery
  • Infectious Diseases

Background:

  • Spinal tuberculosis presents unique challenges for assessing structural instability.
  • The Spinal Instability Neoplastic Score (SINS) is validated for neoplastic conditions but its utility in spinal tuberculosis is unexplored.

Purpose of the Study:

  • To evaluate the feasibility and effectiveness of the SINS score in assessing structural instability in patients with spinal tuberculosis.
  • To determine if SINS scoring can aid in surgical decision-making for spinal tuberculosis management.

Main Methods:

  • A prospective observational study included 80 patients diagnosed with spinal tuberculosis.
  • Patients were classified into stable, indeterminate, and unstable groups using the SINS score.
  • Treatment decisions (surgical vs. non-surgical) were based on SINS classification and clinical parameters.

Main Results:

  • SINS classification identified 7 stable, 45 indeterminate, and 28 unstable cases.
  • All unstable patients underwent surgery; none of the stable patients required surgery.
  • In the indeterminate group, 26 of 45 patients had surgery, primarily due to pain and neurological status.
  • Significant improvements in pain (VAS) and disability (ODI) were observed post-surgery and with non-operative management in the indeterminate group.

Conclusions:

  • The SINS score is a valuable tool for guiding surgical decisions in spinal tuberculosis.
  • Further validation with larger, multicenter studies is recommended to refine the SINS score for spinal tuberculosis.