Related Experiment Video

Updated: Oct 28, 2025

Generation, Amplification, and Titration of Recombinant Respiratory Syncytial Viruses
11:48

Generation, Amplification, and Titration of Recombinant Respiratory Syncytial Viruses

Published on: April 4, 2019

16.5K

Delayed Bronchiolitis Epidemic in French Primary Care Setting Driven by Respiratory Syncytial Virus: Preliminary Data

Alexis Rybak1,2,3,4, Corinne Levy1,2,5,6, Camille Jung4

  • 1From ACTIV, Association Clinique et Thérapeutique Infantile du Val-de-Marne, Créteil, France.

The Pediatric Infectious Disease Journal
|July 14, 2021
PubMed

Insights

A French study found a delayed 2021 bronchiolitis epidemic. Respiratory Syncytial Virus (RSV) was the primary cause in 55% of young children, with no influenza cases detected.

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Epidemiology

Background:

  • Bronchiolitis is a common viral respiratory infection in infants.
  • Surveillance of respiratory pathogens is crucial for public health planning.
  • The COVID-19 pandemic potentially impacted seasonal respiratory virus circulation.

Purpose of the Study:

  • To monitor bronchiolitis epidemiology in primary care settings.
  • To identify the causative agents of infant bronchiolitis during the 2020-2021 season.
  • To assess the impact of the pandemic on respiratory virus epidemics.

Main Methods:

  • Prospective surveillance study conducted in French primary care.
  • Inclusion of 225 children under 2 years with a first episode of bronchiolitis.
  • Swab testing for respiratory pathogens including RSV, influenza, and SARS-CoV-2.

Main Results:

  • A 10-week delayed bronchiolitis epidemic occurred from February to March 2021.
  • Respiratory Syncytial Virus (RSV) was detected in 55% of tested children.
  • No influenza cases were identified; one case of SARS-CoV-2 was detected.

Conclusions:

  • RSV remained the predominant cause of infant bronchiolitis despite the pandemic.
  • The study highlights a significant delay in the typical bronchiolitis epidemic season.
  • Ongoing surveillance is essential to understand evolving respiratory virus patterns.

More Related Videos

An In vitro Model to Study Immune Responses of Human Peripheral Blood Mononuclear Cells to Human Respiratory Syncytial Virus Infection09:01

An In vitro Model to Study Immune Responses of Human Peripheral Blood Mononuclear Cells to Human Respiratory Syncytial Virus Infection

Published on: December 10, 2013

8.0K
An Improved and High Throughput Respiratory Syncytial Virus RSV Micro-neutralization Assay09:14

An Improved and High Throughput Respiratory Syncytial Virus RSV Micro-neutralization Assay

Published on: January 26, 2019

11.2K

Related Concept Videos

Common Respiratory Disorders01:31

Common Respiratory Disorders

Respiratory disorders, a prevalent health concern globally, are generally divided into two primary categories: upper and lower respiratory tract disorders. The categorization is based on the area of the respiratory system they affect.
Upper respiratory disorders impact the airways above the vocal cords, encompassing areas like the nose, sinuses, and throat. Various conditions fall under this category, including the common cold and allergic rhinitis. These disorders can stem from several causes,...
1.0K
Acute Respiratory Failure-I01:21

Acute Respiratory Failure-I

Acute respiratory failure is a condition characterized by the inability of the lungs to perform their primary function: gas exchange. This failure leads to insufficient oxygen levels (hypoxemia) in the blood, elevated carbon dioxide levels (hypercapnia), or both, causing critical impairment in organ function.
Definition: It is defined by specific criteria based on blood gas measurements. Hypoxemia happens when the partial pressure of oxygen (PaO2) falls below 60 mmHg. At the same time,...
451
Acute Respiratory Failure-V01:29

Acute Respiratory Failure-V

The treatment for acute respiratory failure varies based on factors like the underlying cause, overall health, and severity. A collaborative healthcare team is essential for early detection, often through arterial blood gas analysis. Identifying the cause is the primary goal, with treatment strategies adjusted for ventilation/perfusion (V/Q) mismatch, shunting, or diffusion impairment.
Ensure that patients are monitored continuously for their response to therapy, including changes in...
250
Acute Respiratory Failure-II01:21

Acute Respiratory Failure-II

Type I Respiratory Failure, or hypoxemic respiratory failure, occurs when the partial pressure of oxygen (PaO2) in arterial blood falls below 60 mmHg while breathing room air without a corresponding increase in arterial carbon dioxide levels (PaCO2). This condition highlights a significant impairment in the lungs' capacity to oxygenate the blood.
The underlying physiological abnormalities that contribute to hypoxemic respiratory failure include:
552
Acute Pharyngitis01:30

Acute Pharyngitis

Introduction
Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
Classification
Acute pharyngitis can be categorized based on its underlying cause:
2.2K
Acute Respiratory Failure-III01:30

Acute Respiratory Failure-III

Hypercapnic respiratory failure, also known as Type 2 or ventilatory respiratory failure, is a severe condition characterized by the body's inability to effectively remove carbon dioxide (CO2) from the bloodstream. It leads to an arterial CO2 pressure (PaCO2) exceeding 45 mmHg and a blood pH above 7.35. This situation indicates that the body's ventilatory demand, or the ventilation needed to maintain normal PaCO2 levels, surpasses its supply or the maximum gas flow achievable without...
422