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Structure and dynamics of semaglutide- and taspoglutide-bound GLP-1R-Gs complexes

Xin Zhang1, Matthew J Belousoff1, Yi-Lynn Liang2

  • 1Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville 3052, VIC, Australia; ARC Centre for Cryo-electron Microscopy of Membrane Proteins, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville 3052, VIC, Australia.

Cell Reports
|July 14, 2021
PubMed

Keywords:
GLP-1RGPCR dynamicsGPCRscryoelectron microscopyglucagon-like peptide-1 receptorsemaglutidetasopglutide

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