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Preliminary Study on Acupuncture Combined with Grain-sized Moxibustion for Treating Rheumatoid Arthritis with Finger Joint Pain
Published on: May 16, 2025
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Intradermal acupuncture for rheumatoid arthritis: study protocol for a randomised controlled trial
Huifang Luo1, Jie Peng1, Qing Ma1
1School of Nursing, Guangzhou University of Chinese Medicine, Guangzhou, 510405, Guangdong Province, China.
Trials
|July 15, 2021
Summary
This study investigates intradermal acupuncture (IA) for rheumatoid arthritis (RA). It explores IA
Area of Science:
- Rheumatology
- Integrative Medicine
- Traditional Chinese Medicine
Background:
- Rheumatoid arthritis (RA) is a prevalent autoimmune condition significantly impairing patient quality of life.
- Current RA treatments carry notable adverse side effects.
- Intradermal acupuncture (IA) shows promise as a safe and feasible therapeutic option, yet its efficacy in RA management remains unexamined.
Purpose of the Study:
- To evaluate the efficacy and safety of intradermal acupuncture (IA) as a treatment for rheumatoid arthritis (RA).
- To provide high-quality evidence for IA's application in RA patient care.
- To offer references for acupoint selection in managing other Traditional Chinese Medicine (TCM) syndromes.
Main Methods:
- A randomized, sham-controlled, blinded trial involving 132 adult RA patients.
- Participants allocated 1:1 to receive either IA or sham IA alongside standard RA care.
- Primary outcomes included TCM syndromes and Health Assessment Questionnaire (HAQ) scores; secondary outcomes were DAS28 and serum CRP levels, assessed pre- and post-treatment.
Main Results:
- This section is to be filled once the study is completed and results are available.
Conclusions:
- This study is designed to generate robust evidence regarding the effectiveness and safety of IA for rheumatoid arthritis.
- Findings will inform clinical practice and potentially guide acupoint selection for related conditions.

