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Assessment and Management of Diabetic Patients During the COVID-19 Pandemic

Amit K Verma1, Mirza Masroor Ali Beg2, Deepti Bhatt1

  • 1Medical Biotechnology Lab, Department of Biotechnology, Jamia Millia Islamia, New Delhi, India.

Diabetes, Metabolic Syndrome and Obesity : Targets and Therapy
|July 15, 2021
PubMed

Insights

COVID-19 poses significant challenges, especially for individuals with diabetes mellitus (DM). This review explores how diabetes impacts COVID-19 severity and discusses management strategies for these patients.

Area of Science:

  • Infectious Diseases
  • Endocrinology
  • Public Health

Background:

  • COVID-19 presents a global health challenge, particularly impacting developing nations.
  • Diabetes Mellitus (DM), hypertension, and cardiovascular diseases are common comorbidities with COVID-19.
  • Elevated blood glucose levels are frequently observed in COVID-19 patients, especially those with type 2 diabetes mellitus (T2DM).

Purpose of the Study:

  • To elucidate the mechanisms linking COVID-19 and DM.
  • To investigate the role of Angiotensin-Converting Enzyme 2 (ACE2) in COVID-19 pathogenesis among diabetic patients.
  • To review management strategies for DM and its complications in the context of COVID-19.

Main Methods:

  • This study is a comprehensive literature review.
  • It synthesizes existing research on COVID-19, diabetes, and related comorbidities.
  • The review focuses on understanding pathogenic mechanisms and clinical management.

Main Results:

  • Diabetes is a significant risk factor for increased COVID-19 severity and mortality.
  • Dysregulated immune response in diabetic patients exacerbates COVID-19.
  • Chronic conditions and altered ACE2 expression contribute to higher risk in diabetic individuals.

Conclusions:

  • Diabetic patients face heightened risks for severe COVID-19 outcomes.
  • Effective management requires addressing both COVID-19 and underlying diabetic comorbidities.
  • Further understanding of COVID-19-DM interactions is crucial for clinical practice, especially in vulnerable populations.

Keywords:
COVID-19Indiacardiovascular diseasesdiabeteshypertension

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