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Related Experiment Video

Updated: Jul 12, 2026

Intraspinal Cell Transplantation for Targeting Cervical Ventral Horn in Amyotrophic Lateral Sclerosis and Traumatic Spinal Cord Injury
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Late Discovering Spina Ventosa: A Case Report.

Sang Nguyen Ngoc1, Ha Nguyen Thai1, Quang Vu Van1

  • 1Haiphong University of Medicine and Pharmacy, Hai Phong, Vietnam.

International Medical Case Reports Journal
|July 15, 2021
PubMed
Summary

Spina Ventosa, a rare bone tuberculosis, can cause severe systemic symptoms if misdiagnosed. Prompt treatment led to a full recovery in a 7-year-old boy with late-diagnosed osteoarticular tuberculosis.

Keywords:
childrenosteo-articular tuberculosisspina ventosa

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Area of Science:

  • Pediatric Infectious Diseases
  • Orthopedic Tuberculosis
  • Diagnostic Challenges in Rare Diseases

Background:

  • Spina Ventosa, a rare manifestation of osteoarticular tuberculosis, often presents with diagnostic challenges.
  • Delayed diagnosis can lead to severe systemic complications beyond skeletal involvement.

Observation:

  • A 7-year-old boy presented with painless swelling and sinus discharge, initially misdiagnosed.
  • Clinical presentation included severe anemia, pleural effusion, and ascites, alongside bone lesions.
  • Diagnostic workup revealed positive QuantiFERON-TB, characteristic radiographic findings, and confirmed tuberculosis via histopathology.

Findings:

  • The patient exhibited extensive osteoarticular tuberculosis with systemic involvement.
  • Histopathological examination confirmed tuberculosis in bone, pleural, and ascitic fluid samples.
  • Radiographic evidence showed cortical destruction, sclerosis, and cystic expansion of metacarpals and phalanges.

Implications:

  • Early recognition and prompt treatment of Spina Ventosa are crucial to prevent severe systemic sequelae.
  • Aggressive multi-drug anti-tuberculosis therapy can lead to complete resolution of complex cases.
  • This case highlights the importance of considering tuberculosis in pediatric bone swellings, even in the absence of typical risk factors.