Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Ultrasound II: Endoscopic Ultrasound and FibroScan

Ultrasound II: Endoscopic Ultrasound and FibroScan

Endoscopic Ultrasound (EUS) and FibroScan are valuable diagnostic tools in gastroenterology and hepatology, each with specific applications and techniques.
Endoscopic Ultrasound (EUS):

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Portopulmonary Hypertension: Current Perspectives.

Heart failure clinics·2026

Same author

A HDL-based cirrhosis risk score improves the prediction of short-term mortality in acutely decompensated cirrhosis.

Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·2026

Same author

MyBioScope: a new frontier in gut microbiome and health research.

Bioresources and bioprocessing·2026

Same author

Post-Radiation PET Shows Higher Diagnostic Accuracy in HPV-Negative Head and Neck Cancers.

Cancers·2026

Same author

Prognostic Value of Exercise Testing in Patients with Liver Cirrhosis.

Diagnostics (Basel, Switzerland)·2026

Same author

Single-cell, clonal and spatial atlases of cranial placodes illuminate their specification and evolution.

bioRxiv : the preprint server for biology·2026

Search research articles

Related Experiment Video

Updated: Oct 28, 2025

Author Spotlight: Assessing Surgical Frailty with Point-of-Care Ultrasound of Quadriceps Muscles

Author Spotlight: Assessing Surgical Frailty with Point-of-Care Ultrasound of Quadriceps Muscles

Published on: July 26, 2024

Fibroscan® probe selection for lean adults.

Vanessa Stadlbauer¹, Iohanes Negrean¹, Andreas Posch¹

¹Division of Gastroenterology and Hepatology, Department of Internal Medicine Medical University of Graz Graz Austria.

JGH Open : an Open Access Journal of Gastroenterology and Hepatology

|July 15, 2021

Summary

This summary is machine-generated.

FibroScan® probes S+ and M+ can assess liver stiffness in lean adults with a thoracic circumference (TC) ≤75 cm. A light meal before the noninvasive liver assessment does not impact results.

Keywords:

agreement bias examination liver stiffness meal preparation steatosis thoracic circumference transient elastography

More Related Videos

Focused Assessment with Sonography for Trauma FAST Exam: Image Acquisition

Focused Assessment with Sonography for Trauma FAST Exam: Image Acquisition

Published on: September 22, 2023

Implementation of Non-invasive Point of Care Transient Elastography for Evaluation of Liver Disease in Pediatric Populations with Cystic Fibrosis

Implementation of Non-invasive Point of Care Transient Elastography for Evaluation of Liver Disease in Pediatric Populations with Cystic Fibrosis

Published on: August 29, 2025

Related Experiment Videos

Last Updated: Oct 28, 2025

Author Spotlight: Assessing Surgical Frailty with Point-of-Care Ultrasound of Quadriceps Muscles

Author Spotlight: Assessing Surgical Frailty with Point-of-Care Ultrasound of Quadriceps Muscles

Published on: July 26, 2024

Focused Assessment with Sonography for Trauma FAST Exam: Image Acquisition

Focused Assessment with Sonography for Trauma FAST Exam: Image Acquisition

Published on: September 22, 2023

Implementation of Non-invasive Point of Care Transient Elastography for Evaluation of Liver Disease in Pediatric Populations with Cystic Fibrosis

Implementation of Non-invasive Point of Care Transient Elastography for Evaluation of Liver Disease in Pediatric Populations with Cystic Fibrosis

Published on: August 29, 2025

Area of Science:

Hepatology
Medical Imaging
Noninvasive Diagnostics

Background:

FibroScan® is a noninvasive tool for assessing liver fibrosis and steatosis.
Manufacturer guidelines recommend specific probes (S+ or M+) based on patient age and thoracic circumference (TC).
No comparative studies exist for lean adults with TC ≤75 cm, and fasting requirements are unclear.

Purpose of the Study:

To compare FibroScan® S+ and M+ probes for liver stiffness (LS) and controlled attenuation parameter (CAP) in healthy adults with TC ≤75 cm versus TC >75 cm.
To evaluate the impact of fasting versus a light meal on LS and CAP measurements in these groups.

Main Methods:

Compared LS using FibroScan® S+ and M+ probes in 50 healthy volunteers stratified by TC (≤75 cm vs. >75 cm).
Assessed CAP using the M+ probe.
Evaluated measurements in both fasting state and after a standardized light meal (300 kcal).

Main Results:

LS values were consistently 15% higher with the S+ probe compared to the M+ probe across both TC groups (P < 0.001).
Both probes demonstrated good agreement and minimal bias (Spearman's r = 0.754, ICC = 0.843).
A light meal did not significantly influence LS or CAP measurements in either group.

Conclusions:

Lean adults with a TC ≤75 cm can be accurately assessed for liver stiffness using either the S+ or M+ probe.
Fasting is not required; a light meal can be consumed before FibroScan® assessment in this population.