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Related Concept Videos

The Vestibular System01:29

The Vestibular System

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The vestibular system is a set of inner ear structures that provide a sense of balance and spatial orientation. This system is comprised of structures within the labyrinth of the inner ear, including the cochlea and two otolith organs—the utricle and saccule. The labyrinth also contains three semicircular canals—superior, posterior, and horizontal—that are oriented on different planes.
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The inner ear assumes dual functionalities of auditory perception and equilibrium maintenance. The vestibule is the organ responsible for balance. This organ contains mechanoreceptors, specifically hair cells, endowed with stereocilia, which aid in deciphering information regarding the position and motion of our heads. Two intrinsic components, the utricle and saccule, help perceive head position, while the semicircular canals track head movement. Neurological messages initiated in the...
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Sensory impulses related to touch, pressure, vibration, and proprioception from various body parts, such as the limbs, trunk, neck, and posterior head, travel to the cerebral cortex through the posterior column-medial lemniscus pathway. The pathway’s name derives from the two white-matter tracts that convey the impulses: the spinal cord's posterior column and the brainstem's medial lemniscus. First-order sensory neurons extend their axons into the spinal cord, forming the...
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The indirect motor or extrapyramidal pathways originate in the brainstem, the lower portion of the brain that connects it to the spinal cord. They consist of several distinct tracts, each with specialized functions. The four main tracts of the indirect motor pathways are the vestibulospinal tract, the reticulospinal tract, the tectospinal tract, and the rubrospinal tract.
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Articles linked to this work by shared authors, journal, and citation graph.

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Comparison of Quality of Life Between Patients with Chronic Unilateral Vestibular Hypofunction and Bilateral Vestibulopathy.

The journal of international advanced otology·2026
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Unperturbed and perturbed gait variability is increased in bilateral vestibulopathy compared with age- and sex-matched healthy participants.

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Using the probability of recovery from an acute unilateral vestibulopathy to determine the severity of the vestibular loss: Development of a multivariate PROBIT model.

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Related Experiment Video

Updated: Oct 28, 2025

Using Unidirectional Rotations to Improve Vestibular System Asymmetry in Patients with Vestibular Dysfunction
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Using Unidirectional Rotations to Improve Vestibular System Asymmetry in Patients with Vestibular Dysfunction

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Bilateral vestibulopathy decreases self-motion perception.

Lisa van Stiphout1, Florence Lucieer2, Maksim Pleshkov2,3

  • 1Department of Otorhinolaryngology and Head and Neck Surgery, Division of Balance Disorders, School for Mental Health and Neuroscience, Maastricht University Medical Center, P. Debyelaan 25, 6229 HX, Maastricht, The Netherlands. lisa.van.stiphout@mumc.nl.

Journal of Neurology
|July 15, 2021
PubMed
Summary

Bilateral vestibulopathy (BV) patients show significantly impaired self-motion perception compared to healthy individuals. This decreased perception correlates with reduced residual vestibular function in BV patients.

Keywords:
Bilateral vestibulopathyPerceptionPerceptual self-motion thresholdsSelf-motion perceptionThresholdVestibular

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Area of Science:

  • Neuroscience
  • Otolaryngology
  • Vestibular System Research

Background:

  • Current diagnostic criteria for bilateral vestibulopathy (BV) rely on vestibular reflex measurements.
  • Perceptual self-motion thresholds are not routinely assessed in BV patients.
  • The clinical utility of self-motion perception testing in BV remains undetermined.

Purpose of the Study:

  • To compare perceptual self-motion thresholds between BV patients and control subjects.
  • To investigate the relationship between self-motion perception and vestibular function in BV patients.

Main Methods:

  • Thirty-seven BV patients and 34 controls participated.
  • Perceptual self-motion thresholds were measured using a CAREN platform.
  • Vestibular function was assessed via caloric, torsion swing, video head impulse tests, and VEMPs in BV patients.

Main Results:

  • BV patients exhibited significantly higher perceptual self-motion thresholds than controls across most rotations and translations.
  • Cluster analysis revealed that higher thresholds in BV patients correlated with poorer results on vestibular function tests (yaw rotation, caloric, torsion swing, vHIT).

Conclusions:

  • Self-motion perception is significantly diminished in BV patients.
  • Impaired self-motion perception in BV is associated with reduced residual vestibular function.