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Updated: Oct 28, 2025

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies
Published on: February 6, 2019
Primary bilateral angiosarcoma of the breast treated with neoadjuvant chemotherapy combined with propranolol
Elzbieta Luczynska1, Wojciech Rudnicki2, Jaromir Kargol1
1Faculty of Medicine, University of Rzeszow, Rzeszow, Poland.
Abstract:
A case report of bilateral primary angiosarcoma treated with neoadjuvant chemotherapy was presented. A routine diagnostic mammography and ultrasound examinations indicated abnormalities in both breasts of the patient, confirmed on MRI as large bilateral masses. Core needle biopsy revealed angiosarcoma G1. The treatment agreed during the interdisciplinary meeting involved chemotherapy combined with simultaneous blockade of beta-adrenergic receptors, followed by bilateral simple mastectomy. This case highlights the importance of a patient-focused care.
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