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Updated: Oct 28, 2025

Tissue Preparation Techniques for Contrast-Enhanced Micro Computed Tomography Imaging of Large Mammalian Cardiac Models with Chronic Disease
Published on: February 8, 2022
[IS MYOCARDIAL PERFUSION IMAGING INTERPRETATION HARDER WITH X-RAY BEAM HARDENING ARTIFACT?]
Tala Palchan Hazan1, Samia Massalha2, John Kennedy3
1Nuclear Medicine Institute, Rambam Health Care Campus.
Introduction:
Myocardial perfusion imaging (MPI) is a well-established imaging modality for the diagnosis of coronary artery disease and for prognostication. In recent years, the management of heart failure has developed tremendously including implantation of defibrillators for prevention of malignant tachyarrhythmias and resynchronizing therapy for the improvement of clinical symptoms and left ventricular function. Cardiac magnetic resonance and computed tomography are imaging modalities that are negatively affected by the presence of metallic devices. MPI is a hybrid study combining computed tomography for attenuation correction and nuclear imaging. This case shows that a metal device has no effect on the interpretation of MPI.
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