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Published on: November 3, 2023
Risk factor analysis of acute kidney injury after one-stop hybrid coronary revascularization
Dongjie Li1, Jie Gao1, Yulin Guo1
1Department of Cardiac Surgery, Heart Center, Beijing Chaoyang Hospital, Capital Medical University, Beijing, China.
Insights
One-stop hybrid coronary revascularization (HCR) did not raise acute kidney injury (AKI) rates. Advanced age and perioperative transfusions are key risk factors for AKI following HCR procedures.
Area of Science:
- Cardiology
- Nephrology
- Surgical Innovation
Background:
- One-stop hybrid coronary revascularization (HCR) integrates coronary artery bypass grafting (CABG) and percutaneous coronary intervention (PCI).
- Acute kidney injury (AKI) is a known complication following CABG and PCI.
- The incidence and risk factors of AKI after one-stop HCR remain to be fully elucidated.
Purpose of the Study:
- To investigate the incidence of postoperative AKI after one-stop HCR.
- To identify independent risk factors associated with AKI development in patients undergoing one-stop HCR.
Main Methods:
- A retrospective analysis of 123 consecutive patients undergoing one-stop HCR.
- Patients were categorized into AKI (n=11) and non-AKI (n=112) groups.
- Baseline characteristics and perioperative variables were statistically analyzed to determine risk factors.
Main Results:
- The incidence of postoperative AKI was 8.9% (11 patients).
- Patients in the AKI group were significantly older, had higher preoperative creatinine, greater postoperative drainage, higher rates of chronic renal insufficiency, and received more perioperative transfusions.
- Advanced age (≥75 years) and perioperative transfusions were identified as independent risk factors for AKI.
Conclusions:
- One-stop HCR did not appear to increase the incidence of postoperative AKI in this cohort.
- Advanced age and perioperative transfusions are significant independent risk factors for AKI post-HCR.
- Further research is warranted to validate these findings and refine AKI risk prediction in HCR patients.
Background:
One-stop hybrid coronary revascularization (HCR) combines coronary artery bypass grafting (CABG) and percutaneous coronary intervention (PCI) procedures simultaneously. Acute kidney injury (AKI) is a common complication after CABG or PCI. This study explored the risk factors for developing AKI after one-stop HCR.
Methods:
A total of 123 consecutive patients who underwent one-stop HCR between April 2018 and November 2020 were included in this single-center retrospective study. Postoperative AKI was observed in 11 patients (the AKI group), and 112 patients did not develop postoperative AKI (the non-AKI group). Baseline characteristics and perioperative variables were extracted from the electronic medical records and statistically analyzed.
Results:
Postoperative AKI occurred in 11 (8.9%) patients. Compared to patients who did not develop AKI, patients in the AKI group were older (71.0±9.5 vs. 64.1±9.2 years, P=0.019), had higher preoperative creatinine levels (92.6±16.8 vs. 69.8±14.4 mmol/L, P<0.001), experienced a greater volume of postoperative drainage on the first day {850 mL [410, 1,500] vs. 500 mL [321, 700], P=0.045}, had a higher proportion of chronic renal insufficiency (eGFR <60 mL/min/1.73 m2) (36.4% vs. 7.1%, P=0.012), and had more perioperative transfusions (63.6% vs. 22.3%, P=0.007). Multivariate logistics analyses revealed that advanced age [odds ratio (OR) 5.44, P=0.014] and perioperative transfusions (OR 4.62, P=0.028) were independent risk factors for developing AKI after one-stop HCR.
Conclusions:
One-stop HCR did not increase the incidence of postoperative AKI in our center. Advanced age (≥75 years) and perioperative transfusions were independent risk factors for developing AKI after one-stop HCR. Further studies need to be conducted to confirm the risk factors of AKI after HCR procedures.
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