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Related Concept Videos

Drugs for Treatment of Constipation-Predominant IBS01:21

Drugs for Treatment of Constipation-Predominant IBS

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Pharmacological therapies for IBS-C are designed to alleviate abdominal discomfort and enhance bowel function. In patients with IBS-C, fiber supplements may help soften stools and decrease straining, but may also lead to increased gas production and bloating. Osmotic laxatives like milk of magnesia are frequently used to soften stools and increase stool frequency in IBS-C patients. In addition, two drugs approved for use in severe IBS-C adult cases are linaclotide (Linzess) and lubiprostone...
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Drugs for Treatment of Diarrhea-Predominant IBS01:17

Drugs for Treatment of Diarrhea-Predominant IBS

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Diarrhea-predominant irritable bowel syndrome (IBS-D) is a subtype of IBS characterized primarily by frequent, loose, or watery stools, abdominal pain, and abdominal discomfort. Therapeutic approaches to managing IBS-D include dietary changes, stress management techniques, and pharmaceutical interventions.
Two specific drugs used in the treatment are alosetron (Lotronex) and eluxadoline (Viberzi). Alosetron, a 5-HT3 antagonist, works by slowing the movement of stools in the gut, reducing bowel...
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Drugs Affecting GI Tract Motility: Bulk-Forming and Stimulant Laxatives01:22

Drugs Affecting GI Tract Motility: Bulk-Forming and Stimulant Laxatives

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Laxatives enhance bowel movements and alleviate constipation. They augment the stool's bulk, stimulate intestinal muscle contractions, draw water into the intestines, or soften the stool. There are five key types of laxatives: bulk laxatives, stimulant laxatives, osmotic laxatives, stool softeners, and lubricant laxatives.
Bulk-forming laxatives, such as psyllium, methylcellulose, and polycarbophil, absorb water in the intestine, increasing stool bulk and promoting bowel movement. This...
361
Drugs Affecting GI Tract Motility: Other Laxatives01:20

Drugs Affecting GI Tract Motility: Other Laxatives

634
Laxatives are primarily used to alleviate constipation, a common gastrointestinal disorder characterized by infrequent bowel movements and difficulty passing stools. They work by various mechanisms to increase the volume or frequency of bowel movements. The primary modes of action of laxatives include increasing stool bulk, softening the stool, stimulating intestinal motility, and osmotically drawing water into the intestines.
Osmotic or saline laxatives, like magnesium hydroxide or milk of...
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Irritable Bowel Syndrome III: Medical and Nursing Management01:30

Irritable Bowel Syndrome III: Medical and Nursing Management

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Managing Irritable Bowel Syndrome (IBS) involves a multifaceted approach, including lifestyle modifications, dietary changes, and medication.
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Drugs Affecting GI Tract Motility: Adsorbents as Antidiarrheal Agents01:20

Drugs Affecting GI Tract Motility: Adsorbents as Antidiarrheal Agents

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Diarrhea is characterized by the occurrence of frequent, watery bowel movements. Various factors can trigger diarrhea, including viral or bacterial infections, foodborne illnesses, side effects from certain medications, and underlying digestive disorders. If not adequately managed, diarrhea can lead to complications such as dehydration, electrolyte imbalances, and nutrient deficiencies. Severe diarrhea can lead to significant weight loss, malnutrition, and weakened immune function.
Adsorbents...
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Electroacupuncture Combined with Chinese Medicine Ironing Therapy for Functional Constipation
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Acupuncture methods for functional constipation: protocol for a systematic review and network meta-analysis.

Junpeng Yao1, Liping Chen1, Siyuan Zhou1

  • 1Acupuncture and Tuina School, Chengdu University of Traditional Chinese Medicine, Chengdu, China.

Annals of Palliative Medicine
|July 15, 2021
PubMed
Summary
This summary is machine-generated.

This study will compare acupuncture methods for functional constipation (FC). It aims to rank therapies by effectiveness and safety, aiding treatment decisions for this common gastrointestinal disorder.

Keywords:
Functional constipation (FC)acupuncture therapynetwork meta-analysis (NMA)

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Area of Science:

  • Gastroenterology and Hepatology
  • Integrative and Complementary Medicine
  • Clinical Trial Methodology

Background:

  • Functional constipation (FC) is a prevalent gastrointestinal disorder significantly impacting quality of life.
  • Existing research suggests acupuncture's efficacy for FC, but comparative effectiveness of different methods is unclear.
  • This study protocol addresses the need to evaluate and rank various acupuncture approaches for FC treatment.

Purpose of the Study:

  • To systematically assess and rank the effectiveness and safety of diverse acupuncture methods for treating functional constipation.
  • To provide an evidence-based hierarchy of acupuncture therapies for FC management.
  • To support informed treatment decisions for healthcare providers and patients.

Main Methods:

  • A comprehensive search of 8 bibliographic databases (inception to June 2021) for randomized controlled trials (RCTs) on acupuncture for FC.
  • Primary outcome: weekly stool frequency (BM, SBM, complete SBM). Bayesian network meta-analysis using ADDIS V.1.16.8.
  • Systematic review methodology including risk of bias assessment and GRADE for evidence appraisal; meta-regression and subgroup analyses planned.

Main Results:

  • This section is not applicable for a protocol study.
  • Results will be determined after data synthesis and analysis.
  • The study aims to establish comparative effectiveness and safety rankings.

Conclusions:

  • This study will provide evidence-based hierarchies for acupuncture therapies in managing functional constipation.
  • Findings will assist clinicians and patients in selecting the most effective and safe acupuncture treatments.
  • The research aims to optimize FC management through comparative analysis of acupuncture modalities.