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Updated: Oct 28, 2025

Athymic Rat Model for Evaluation of Engineered Anterior Cruciate Ligament Grafts
Published on: March 26, 2015
[Should allografts become gold-standard in ligamentous knee surgery ?]
Philippe M Tscholl1,2,3, Jacques Menetrey1,4, Morgan Gauthier1,2
1Service de chirurgie orthopédique et de traumatologie de l'appareil locomoteur, HUG, 1211 Genève 14.
Abstract:
Allografts in reconstructive knee surgery are an interesting option, due to the absence of donor site morbidity, its rather easy intraoperative handling, the different sizes, shorter surgical time, and therefore less peroperative risks. The risk of infection is very low. Their results are similar when non-irradiated and non-sterilized allografts are used in terms of postoperative strength, return to sport, and comparable stability testing. Nevertheless, allografts have not yet become current practice, due to the costs, the availability, its structural integration and ligamentisation process that might be prolonged and its increased re-rupture rate in the young and active population. Its undeniable value for multiligamentous or complexe knee reconstruction is however undeniable, which should however be reserved for specialized centers.

